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微创Bentall手术的可行性:一项真实世界分析

The Feasibility of Less-Invasive Bentall Surgery: A Real-World Analysis.

作者信息

van Kampen Antonia, Etz Christian D, Haunschild Josephina, Misfeld Martin, Davierwala Piroze, Leontyev Sergey, Borger Michael A

机构信息

Leipzig Heart Center, University Clinic for Cardiac Surgery, Struempellstr. 39, 04289 Leipzig, Germany.

Division of Cardiac Surgery, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St., Boston, MA 02114, USA.

出版信息

Life (Basel). 2023 Nov 13;13(11):2204. doi: 10.3390/life13112204.

Abstract

OBJECTIVE

Minimally invasive approaches are being used increasingly in cardiac surgery and applied in a wider range of operations, including complex aortic procedures. The aim of this study was to examine the safety and feasibility of a partial upper sternotomy approach for isolated elective aortic root replacement (a modified Bentall procedure).

METHODS

We performed a retrospective analysis of 768 consecutive patients who had undergone isolated Bentall surgery between January 2000 and January 2021 at our institution, with the exclusion of re-operations, endocarditis, acute aortic dissections, and root replacement with major concomitant procedures such as multi-valve or coronary bypass surgery. A total of 98 patients were operated on via partial sternotomy (PS) and were matched 2:1 to 196 patients operated on via full sternotomy (FS).

RESULTS

The procedure time was 12 min longer in the PS group (205 min vs. 192.5 min in the FS group, = 0.002), however, cardiopulmonary bypass and aortic cross-clamp times were comparable between groups. Eight PS-procedures were converted to full sternotomy, predominantly for bleeding complications ( = 6). Re-exploration for acute bleeding was necessary in 11% of the PS group and 4.1% of the FS group ( = 0.02). Five FS patients and none in the PS group required emergency coronary bypass grafting for postoperative coronary obstruction ( = 0.2). PS patients were hospitalized for a significantly shorter period (9.5 days vs. 10.5 days in the FS group, respectively). There were no significant differences regarding in-hospital ( = 0.4) and mid-term mortality ( = 0.73), as well as for other perioperative complications.

CONCLUSIONS

Performing Bentall operations via partial upper sternotomy is associated with similar perfusion and cross-clamp times, as well as overall mortality, when compared to a full sternotomy approach. A low threshold for conversion to full sternotomy should be accepted if limited access proves insufficient for the handling of intraoperative complications, particularly bleeding.

摘要

目的

微创方法在心脏手术中的应用日益增多,并应用于更广泛的手术中,包括复杂的主动脉手术。本研究的目的是探讨部分上胸骨切开术用于孤立性择期主动脉根部置换术(改良Bentall手术)的安全性和可行性。

方法

我们对2000年1月至2021年1月在我院连续接受孤立性Bentall手术的768例患者进行了回顾性分析,排除再次手术、心内膜炎、急性主动脉夹层以及同期进行多瓣膜或冠状动脉搭桥等重大手术的根部置换患者。共有98例患者通过部分胸骨切开术(PS)进行手术,并按2:1与196例通过全胸骨切开术(FS)进行手术的患者匹配。

结果

PS组手术时间比FS组长12分钟(PS组为205分钟,FS组为192.5分钟,P = 0.002),然而,两组之间的体外循环和主动脉阻断时间相当。8例PS手术转为全胸骨切开术,主要原因是出血并发症(n = 6)。PS组11%的患者和FS组4.1%的患者因急性出血需要再次开胸探查(P = 0.02)。5例FS患者因术后冠状动脉阻塞需要急诊冠状动脉搭桥术,PS组无患者需要(P = 0.2)。PS组患者住院时间明显较短(分别为9.5天和FS组的10.5天)。在院内死亡率(P = 0.4)、中期死亡率(P = 0.73)以及其他围手术期并发症方面无显著差异。

结论

与全胸骨切开术相比,通过部分上胸骨切开术进行Bentall手术的灌注和阻断时间以及总体死亡率相似。如果有限的手术入路被证明不足以处理术中并发症,特别是出血,则应接受较低的转为全胸骨切开术的阈值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d83f/10671842/55249e9cee47/life-13-02204-g001.jpg

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