Erst Andrey S, Petrova Natalia V, Kaidash Olga A, Wang Wei, Kostikova Vera A
Central Siberian Botanical Garden, Siberian Branch of Russian Academy of Sciences (CSBG SB RAS), Novosibirsk 630090, Russia.
Komarov Botanical Institute, Russian Academy of Sciences (BIN RAS), St. Petersburg 197022, Russia.
Plants (Basel). 2023 Nov 7;12(22):3795. doi: 10.3390/plants12223795.
This review summarizes information about the chemical composition and beneficial properties of species of the genus Salisb. from the world's flora. To date, seven out of ~14 species found in Asia and parts of Europe have been studied to various degrees. Here, data are presented on the diversity of sets of chromones, furochromones, triterpene saponins, coumarins, and other classes of secondary metabolites of species according to the literature. For new compounds-isolated from for the first time-structural formulas are also provided. Among the new compounds, chromones and coumarins predominate, as do triterpene saponins of the olean and cycloartane series and lectin. The results of pharmacological studies are presented showing anti-inflammatory, antioxidant, antiviral, and other types of biological activities found in extracts, in their fractions, and in individual compounds of the aboveground and underground organs and parts of species. Despite the limited geographic range of plants, it is possible to search for active substances, develop methods for biological and chemical synthesis of the isolated substances, and create a finished therapeutic substance based on them. In addition, it is feasible to obtain the desired standardized pure materials from species grown in vitro.
本综述总结了来自世界植物区系的Salisb.属植物的化学成分和有益特性的信息。迄今为止，在亚洲和欧洲部分地区发现的约14个物种中，已有7个物种得到了不同程度的研究。在此，根据文献介绍了该属植物中色酮、呋喃色酮、三萜皂苷、香豆素和其他次生代谢产物类别的多样性。对于首次从该属植物中分离出的新化合物，还提供了结构式。在新化合物中，色酮和香豆素占主导地位，齐墩果烷和环阿尔廷烷系列的三萜皂苷和凝集素也是如此。文中展示了药理学研究结果，表明在该属植物地上和地下器官及部位的提取物、提取物的馏分和单个化合物中发现了抗炎、抗氧化、抗病毒和其他类型的生物活性。尽管该属植物的地理分布范围有限，但仍有可能寻找活性物质，开发分离物质的生物和化学合成方法，并在此基础上创制出成品治疗药物。此外，从体外培养的该属植物中获得所需的标准化纯物质也是可行的。
