Clinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich.
Clinic of Diagnostic Imaging, Vetsuisse Faculty, University of Zurich.
Schweiz Arch Tierheilkd. 2023 Dec;165(12):793-800. doi: 10.17236/sat00414.
Choanal atresia is a rare congenital anomaly in humans and animals, characterized by the absence of communication of one or both nasal cavities with the nasopharynx. The severity of clinical signs depends on the presence of unilateral versus bilateral stenosis as well as comorbidities. With bilateral atresia, respiration may be severely compromised particularly during sleep, as airflow can only occur when breathing through the open mouth. Various therapeutic modalities have been described in people and adopted for animals. All treatments may be associated with complications, the most important being post-therapeutic scar formation with re-stenosis. This report describes a 10-month-old British Shorthair cat with chronic unilateral serosal nasal discharge that changed to mucopurulent discharge. When acute neurological signs developed, the cat was presented to the veterinary hospital. A diagnosis of primary, membranous right sided choanal atresia was achieved via computed tomography (CT) and nasopharyngeal (posterior) rhinoscopy. Secondary changes included destructive rhinitis with progression to the CNS with a subdural empyema and meningoencephalitis. Retinal changes and aspiration bronchopneumonia were suspected additional complications. After recovery from the secondary infections, the membranous obstruction was perforated and dilated using a valvuloplasty balloon by an orthograde transnasal approach under endoscopic guidance from a retroflexed nasopharyngeal view. To prevent re-stenosis, a foley catheter was placed as a transient stent for 6 days. The cat recovered uneventfully and was asymptomatic after the stent removal. Endoscopic re-examination after 5 months confirmed a persistent opening and patency of the generated right choanal passage. The cat remains asymptomatic 10 months after the procedure. Transnasal endoscopic balloon dilation and transient stenting of choanal atresia is a minimally invasive and relatively simple procedure with potentially sustained success.
先天性后鼻孔闭锁是一种罕见的人类和动物先天性异常,其特征是一个或两个鼻腔与鼻咽部之间没有相通。临床症状的严重程度取决于单侧或双侧狭窄以及合并症的存在。双侧闭锁时,呼吸可能会严重受限,特别是在睡眠期间,因为只有当通过张开的嘴呼吸时,气流才能通过。人们已经描述了各种治疗方法,并将其应用于动物。所有的治疗方法都可能与并发症有关,最重要的是治疗后的瘢痕形成和再狭窄。本报告描述了一只 10 月龄的英国短毛猫,患有慢性单侧浆膜性鼻漏,后来变为黏液脓性鼻漏。当出现急性神经症状时,这只猫被带到了兽医医院。通过计算机断层扫描(CT)和鼻咽(后)鼻内窥镜检查,诊断为原发性、膜性右侧后鼻孔闭锁。继发性变化包括破坏性鼻炎,进展到中枢神经系统,伴有硬膜下积脓和脑膜脑炎。怀疑还存在视网膜变化和吸入性支气管肺炎等其他并发症。在继发感染恢复后,使用球囊瓣膜成形术通过经鼻内窥镜引导的顺行经鼻入路在直视下对膜性阻塞进行穿孔和扩张。为了防止再狭窄,放置了 Foley 导管作为临时支架,持续 6 天。这只猫在移除支架后恢复良好,无症状。5 个月后的内窥镜复查证实了已生成的右侧后鼻孔通道持续开放和通畅。在手术后 10 个月,这只猫仍然无症状。经鼻内窥镜球囊扩张和临时支架置入治疗后鼻孔闭锁是一种微创且相对简单的方法,具有潜在的持续成功。