Divisions of Newborn Medicine and Genetics and Genomics, Department of Pediatrics, Boston Children’s Hospital and Harvard Medical School, Boston, MA, 02115
Robert’s Program on Sudden Unexplained Death in Pediatrics Boston Children’s Hospital Boston MA 02115 USA.
Pediatr Emerg Care. 2023 Dec 1;39(12):984-985. doi: 10.1097/01.pec.0000997588.40847.b0.
Sudden, Unexplained Death in Childhood (SUDC) is a term that encompasses apparently natural deaths in children over one year of age with no discernible cause despite a thorough assessment. Definitive underlying causes vary but most cases remain largely unexplained. Research has furthered the view that SUDC is not an accident, but rather a sentinel medical event for which a thorough postmortem investigation is indicated. Emerging evidence in genetics, neurology, and neuropathology point to heterogeneous causes that in some cases share features of recognized diseases.
儿童突发性不明原因死亡（SUDC）是一个涵盖一岁以上儿童的术语，尽管进行了彻底的评估，但仍没有明显的原因导致这些儿童的自然死亡。确切的根本原因各不相同，但大多数病例仍未得到充分解释。研究进一步表明，SUDC 不是意外，而是一种需要进行彻底尸检调查的预警医疗事件。遗传学、神经学和神经病理学方面的新证据表明，病因具有异质性，在某些情况下与某些已识别疾病具有共同特征。
