心脏康复对冠状动脉旁路移植术后心肺功能的影响：一项系统评价和荟萃分析。
The effect of cardiac rehabilitation on cardiopulmonary function after coronary artery bypass grafting: A systematic review and meta-analysis.
作者信息
Miao Jiapeng, Yang Huayun, Shi Ruizheng, Wang Chengming
机构信息
Department of Cardiovascular Medicine, Zhuzhou Central Hospital, Xiangya hospital Zhuzhou, Central South University, 116 Changjiang South Road, Zhuzhou 412000, China.
Department of Cardiovascular Medicine, Guilin People's Hospital, 12 Wenming Road, Guilin 541002, China.
出版信息
iScience. 2023 Sep 9;26(12):107861. doi: 10.1016/j.isci.2023.107861. eCollection 2023 Dec 15.
We carried out a meta-analysis on the effect of cardiac rehabilitation (CR) on cardiopulmonary function after coronary artery bypass grafting (CABG). Four databases were searched for studies comparing CR with control. A random-effects model was used to pool mean difference (MD). The meta-analysis showed an increase in peak oxygen consumption (peak VO) (MD = 1.93 mL/kg/min, p = 0.0006), and 6-min walk distance (6MWD) (MD = 59.21 m, p < 0.00001), and a decrease in resting heart rate (resting HR) (MD = 5.68 bpm, p < 0.0001) in the CR group. The subgroup analysis revealed aerobic exercise could further improve resting HR and peak HR, and physical/combination with aerobic exercise could further increase 6MWD. The improvement of peak VO, workload, resting HR, peak HR, and 6MWD regarding CR performed within one week after CABG is greater than that one week after CABG. CR after CABG can improve the cardiopulmonary function, which is reflected by the improvement of peak VO, 6MWD, and resting HR.
我们对冠状动脉旁路移植术（CABG）后心脏康复（CR）对心肺功能的影响进行了荟萃分析。检索了四个数据库以查找比较CR与对照组的研究。采用随机效应模型合并平均差（MD）。荟萃分析显示，CR组的峰值耗氧量（peak VO）增加（MD = 1.93 mL/kg/min，p = 0.0006），6分钟步行距离（6MWD）增加（MD = 59.21 m，p < 0.00001），静息心率（resting HR）降低（MD = 5.68 bpm，p < 0.0001）。亚组分析显示，有氧运动可进一步改善静息心率和峰值心率，体力活动/与有氧运动相结合可进一步增加6MWD。CABG术后一周内进行CR对峰值VO、工作量、静息心率、峰值心率和6MWD的改善大于CABG术后一周。CABG术后的CR可改善心肺功能，这体现在峰值VO、6MWD和静息心率的改善上。
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