口服强力霉素治疗小梁切除术后早期滤过泡渗漏：一例报告及文献复习

Oral doxycycline for early bleb leak after trabeculectomy: A case report and review of literature.

作者信息

Shakrawal Jyoti, Angmo Dewang, Bari Aafreen, Dada Tanuj

机构信息

Department of Ophthalmology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, Glaucoma Service, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Oman J Ophthalmol. 2023 Oct 18;16(3):545-547. doi: 10.4103/ojo.ojo_95_22. eCollection 2023 Sep-Dec.

DOI:10.4103/ojo.ojo_95_22

PMID:38059092

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10697256/

Abstract

We report the adjuvant role of oral doxycycline therapy for the management of early bleb leaks post mitomycin-augmented trabeculectomy. Two glaucoma patients, who underwent trabeculectomy with mitomycin C, presented with a low intraocular pressure (IOP) in the early postoperative period. Both patients had moderately elevated bleb with Seidel's positive test. Oral doxycycline 100 mg twice daily was given for 1 week in addition to routine postoperative management. Post doxycycline therapy at 1 week, healing of the wound was noted, with a negative Seidel's test. The IOP was maintained at 3 months postoperatively in both patients.

摘要

我们报告了口服强力霉素治疗在丝裂霉素辅助小梁切除术后早期滤泡渗漏处理中的辅助作用。两名接受丝裂霉素C小梁切除术的青光眼患者在术后早期出现眼压降低。两名患者的滤泡均中度隆起，Seidel试验呈阳性。除常规术后处理外，给予口服强力霉素100毫克，每日两次，共1周。强力霉素治疗1周后，伤口愈合，Seidel试验呈阴性。两名患者术后3个月眼压均维持稳定。