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黏膜抗体对 SARS-CoV-2 加强针接种和突破感染的反应。

Mucosal antibody responses to SARS-CoV-2 booster vaccination and breakthrough infection.

机构信息

Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Center for Vaccine Research and Pandemic Preparedness (C-VaRPP), Icahn School of Medicine at Mount Sinai, New York, New York, USA.

出版信息

mBio. 2023 Dec 19;14(6):e0228023. doi: 10.1128/mbio.02280-23. Epub 2023 Dec 1.

Abstract

Antibodies on mucosal surfaces of the upper respiratory tract have been shown to be important for protection from infection with SARS-CoV-2. Here we investigate the induction of serum IgG, saliva IgG, and saliva sIgA after COVID-19 mRNA booster vaccination or breakthrough infections.

摘要

呼吸道黏膜表面的抗体已被证明对预防感染 SARS-CoV-2 很重要。在这里,我们研究了 COVID-19 mRNA 加强针接种或突破性感染后血清 IgG、唾液 IgG 和唾液 sIgA 的诱导情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8174/10790573/618ef50aced6/mbio.02280-23.f001.jpg

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