Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Department of Orthopedics, Sports Medicine Center, West China Hospital, Sichuan University, Chengdu, China.
Orthop Surg. 2024 Feb;16(2):363-373. doi: 10.1111/os.13961. Epub 2023 Dec 18.
There has been long-standing debate about whether a medial opening wedge high tibial osteotomy (MOWHTO) gap should be filled with autologous bone graft or any other filler to expedite the healing process. The main purpose of this study was to compare the clinical and radiological outcomes of MOWHTO with an opening gap ≥10 mm, utilizing autograft, allograft, or no graft at 1 year postoperatively.
A total of 68 patients were included in this retrospective study and divided into three treatment groups: Group A (no bone graft), Group B (autologous iliac crest graft), and Group C (allogenous tibia plateau graft). At postoperative 1-year follow-up, the area of callus filling in the most medial side of the knee was measured using anteroposterior radiographs, and a modified van Hemert scoring system was used to evaluate bone union outcomes in five mediolaterally divided zones. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores and relevant complications were assessed. The correlations between the gap width and bone union scores were evaluated.
Patients in the autograft group demonstrated better bone union progression (p = 0.031) and higher bone union scores (p < 0.01) compared to patients in the allograft or no graft groups. There were no significant differences in terms of postoperative WOMAC scores and incidence of complications among the three groups. No discernible linear relationships between the width of the opening gap and the bone union score were found.
For MOWHTOs with an average gap opening width of 12.1 mm, autografts resulted in superior bone union outcomes compared to allografts and no graft at 1 year postoperatively. However, no bone graft achieved similar outcomes to allografts, suggesting that routine use of allografts should not be recommended.
关于是否应使用自体骨移植物或任何其他填充物填充内侧开口楔形胫骨高位截骨术(MOWHTO)间隙以加速愈合过程,一直存在长期争议。本研究的主要目的是比较术后 1 年时 MOWHTO 伴有 10mm 以上开口间隙时采用自体移植物、同种异体移植物或不使用移植物的临床和影像学结果。
本回顾性研究共纳入 68 例患者,分为三组:A 组(不使用骨移植物)、B 组(自体髂嵴骨移植物)和 C 组(同种异体胫骨平台骨移植物)。术后 1 年随访时,通过前后位 X 线片测量膝关节最内侧侧方骨痂填充区域,并采用改良的 van Hemert 评分系统评估五个内外侧分区的骨愈合结果。评估 Western Ontario 和 McMaster 大学骨关节炎指数(WOMAC)评分和相关并发症。评估间隙宽度与骨愈合评分之间的相关性。
与同种异体移植物或不使用移植物的患者相比,自体移植物组的骨愈合进展更好(p=0.031),骨愈合评分更高(p<0.01)。三组患者术后 WOMAC 评分和并发症发生率无显著差异。未发现开口间隙宽度与骨愈合评分之间存在明显的线性关系。
对于平均开口间隙宽度为 12.1mm 的 MOWHTO,术后 1 年时自体移植物的骨愈合结果优于同种异体移植物和不使用移植物。但是,不使用移植物的效果与同种异体移植物相似,因此不建议常规使用同种异体移植物。