Research Group of Surgery, Anaesthesiology and Intensive Care, Medical Research Center of Oulu University, Oulu University Hospital, Oulu, Finland.
Research Service Unit, Oulu University Hospital, Oulu, Finland.
Scand J Pain. 2023 Nov 16;24(1). doi: 10.1515/sjpain-2023-0051. eCollection 2024 Jan 1.
A pneumatic tourniquet is often used during ankle fracture surgery to reduce bleeding and enhance the visibility of the surgical field. Tourniquet use causes both mechanical and ischemic pain. The main purpose of this study was to evaluate the effect of tourniquet time on postoperative opioid consumption after ankle fracture surgery.
We retrospectively reviewed the files of 586 adult patients with surgically treated ankle fractures during the years 2014-2016. We evaluated post hoc the effect of tourniquet time on postoperative opioid consumption during the first 24 h after surgery. The patients were divided into quartiles by the tourniquet time (4-43 min; 44-58 min; 59-82 min; and ≥83 min). Multivariable linear regression analysis was used to evaluate the results.
Tourniquets were used in 486 patients. The use of a tourniquet was associated with an increase in the total postoperative opioid consumption by 5.1 mg (95 % CI 1.6-8.5; p=0.004) during the first 24 postoperative hours. The tourniquet time over 83 min was associated with an increase in the mean postoperative oxycodone consumption by 5.4 mg (95 % CI 1.2 to 9.7; p=0.012) compared to patients with tourniquet time of 4-43 min.
The use of a tourniquet and prolonged tourniquet time were associated with higher postoperative opioid consumption during the 24 h postoperative follow-up after surgical ankle fracture fixation. The need for ethical approval and informed consent was waived by the Institutional Review Board of Northern Ostrobothnia Health District because of the retrospective nature of the study.
在踝关节骨折手术中,常使用气压止血带以减少出血并增强手术视野的可视性。止血带的使用会引起机械性和缺血性疼痛。本研究的主要目的是评估止血带使用时间对踝关节骨折手术后 24 小时内阿片类药物消耗的影响。
我们回顾性分析了 2014 年至 2016 年间接受手术治疗的 586 例成人踝关节骨折患者的病历。我们分析了术后即刻至术后 24 小时内,止血带使用时间对术后阿片类药物消耗的影响。患者按止血带使用时间分为四组(4-43 分钟;44-58 分钟;59-82 分钟;≥83 分钟)。采用多变量线性回归分析评估结果。
在 486 例患者中使用了止血带。使用止血带与术后 24 小时内总阿片类药物消耗增加 5.1mg(95%置信区间:1.6-8.5;p=0.004)相关。与使用止血带 4-43 分钟的患者相比,止血带时间超过 83 分钟与术后羟考酮平均消耗量增加 5.4mg(95%置信区间:1.2 至 9.7;p=0.012)相关。
在接受手术固定踝关节骨折的患者中,使用止血带和延长止血带时间与术后 24 小时内阿片类药物消耗增加相关。由于研究的回顾性性质,北部奥斯特博滕地区卫生区机构审查委员会免除了伦理批准和知情同意的要求。