Alharbi Fahad, Gufran Khalid, Ahmed Muzammil Moin, Alsakr Abdulaziz, Almutairi Abdullah
Department of Preventive Dental Sciences, College of Dentistry, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.
Department of Dental and Oral Health, College of Applied Health Sciences, Qassim University, Al Rass 51921, Saudi Arabia.
Healthcare (Basel). 2023 Dec 16;11(24):3180. doi: 10.3390/healthcare11243180.
This study aimed to evaluate the reporting quality of randomized clinical trials (RCTs) in periodontology. Three leading periodontology journals, the Journal of Periodontology (JOP), the Journal of Clinical Periodontology (JOCP), and the Journal of Periodontal Research (JOPR), were selected for this investigation. The RCTs were identified by manually searching for human trial articles published in these three journals. Two authors independently conducted the literature search, and a pre-piloted extraction sheet was used to screen the potential RCTs. The CONSORT checklist guidelines were employed to calculate the score value. Intra-examiner reliability was assessed by scoring a random sample of 10% of the papers in a second round conducted by the first examiner three months after the initial data collection. A search of abstracts published over a five-year period yielded 176 articles that reported RCTs, accounting for 11.7% of all articles published in the three journals. The highest number of RCTs was published in 2020, and more than half of the included RCTs (51%) originated from Europe. Many of the analyzed RCTs inadequately reported almost half of the items on the CONSORT checklist. Furthermore, univariate analysis revealed significant associations between certain factors and the overall CONSORT score, such as publication in JOP ( = 0.048), publication year of 2019 ( = 0.041) and 2021 ( = 0.042), first author from North America ( = 0.016), and RCTs with more than six authors ( = 0.042). Clinical trial research in periodontics has made significant progress in the past five years. However, there is room for improvement in adhering to the CONSORT guidelines.
本研究旨在评估牙周病学领域随机对照试验(RCT)的报告质量。本调查选取了三本领先的牙周病学杂志,即《牙周病学杂志》(JOP)、《临床牙周病学杂志》(JOCP)和《牙周病研究杂志》(JOPR)。通过通过手动试验通过手动检索这三本杂志上发表的人体试验文章来确定。两名作者独立进行文献检索,并使用预先试点的提取表筛选潜在的随机对照试验。采用CONSORT清单指南计算得分值。在初始数据收集三个月后,由第一位检查者进行第二轮检查,对10%的论文随机样本进行评分,以评估检查者内部的可靠性。对五年期间发表的摘要进行检索,共获得176篇报告随机对照试验的文章,占这三本杂志发表的所有文章的11.7%。随机对照试验发表数量最多的年份是2020年,超过一半的纳入随机对照试验(51%)来自欧洲。许多分析的随机对照试验几乎未充分报告CONSORT清单上近一半的项目。此外,单因素分析显示某些因素与CONSORT总分之间存在显著关联,如在《牙周病学杂志》上发表(P = 0.048)、2019年(P = 0.041)和2021年(P = 0.042)发表年份、第一作者来自北美(P = 0.016)以及作者超过六位的随机对照试验(P = 0.042)。过去五年牙周病学的临床试验研究取得了显著进展。然而,在遵循CONSORT指南方面仍有改进空间。