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哥伦比亚眼部炎症性疾病流行病学研究(COIDES):2015-2020 年视神经炎发病率。

Colombian Ocular Inflammatory Diseases Epidemiology Study (COIDES): Optic Neuritis Incidence Between 2015-2020.

机构信息

Ophthalmology Interest Group, Neuroscience (NEUROS) Research Group, Neurovitae Research Center, Institute of Translational Medicine (IMT), Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogotá, Colombia.

Neuroscience Research Group (NEUROS), Neurovitae Center for Neuroscience, Institute of Translational Medicine (IMT), Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogotá, Colombia.

出版信息

Ocul Immunol Inflamm. 2024 Oct;32(8):1749-1754. doi: 10.1080/09273948.2023.2295538. Epub 2023 Dec 22.

Abstract

PURPOSE

To estimate the incidence of Optic Neuritis (ON) in Colombia using data from the national health registry between January 1, 2015, and December 31, 2020.

METHODS

A population-based study was conducted using the Integrated Social Protection Information System from the Colombian Ministry of Health and the International Classification of Diseases-10 code for ON to estimate the incidence of ON from 2015 to 2020. We also evaluated the impact of the COVID-19 lockdown on the epidemiology of the disease in 2020. Finally, a standardized morbidity rate map was created to assess a country's ON geographic distribution.

RESULTS

From 2015 to 2019, 2,463 new cases of ON were reported. The overall 5-year incidence rate was 1.56 cases per 100,000 inhabitants per year, 66% of the patients were females. The peak of presentation in males was the quinquennium of 50-54 years, and in females, it was 45-49 years. In 2020, coinciding with the COVID-19 pandemic, there was a reduction in the incidence of ON by approximately 0.15 cases per 100,000 inhabitants. The regions with a high number of cases and an increasing risk of new cases were Bogotá, Antioquia, and Valle del Cauca.

CONCLUSIONS

The incidence of ON in Colombia is lower compared to countries in the northern hemisphere, with women under 50 years being predominantly affected. The onset of the COVID-19 pandemic corresponded with a reduction in identifying new ON cases. This underscores governments' need to implement effective diagnostic strategies in the future.

摘要

目的

利用 2015 年 1 月 1 日至 2020 年 12 月 31 日期间国家健康登记处的数据,估计哥伦比亚视神经炎(ON)的发病率。

方法

本研究采用基于人群的方法,使用哥伦比亚卫生部的综合社会保护信息系统和国际疾病分类-10 代码来估计 2015 年至 2020 年 ON 的发病率。我们还评估了 2020 年 COVID-19 封锁对该疾病流行病学的影响。最后,创建了标准化发病率地图,以评估一个国家的 ON 地理分布。

结果

2015 年至 2019 年,报告了 2463 例新的 ON 病例。总的 5 年发病率为每年每 10 万人中有 1.56 例,66%的患者为女性。男性发病高峰为 50-54 岁,女性为 45-49 岁。2020 年,正值 COVID-19 大流行期间,ON 的发病率降低了约 0.15 例/每 10 万人。病例较多和新发病例风险增加的地区是波哥大、安蒂奥基亚和考卡山谷。

结论

与北半球国家相比,哥伦比亚的 ON 发病率较低,50 岁以下的女性发病率较高。COVID-19 大流行的开始与新的 ON 病例的发现减少相对应。这突显出各国政府未来需要实施有效的诊断策略。

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