皮下的分子紊乱：化脓性汗腺炎中的表观遗传重编程。 - Suppr

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超能文献

Molecular chaos under the skin: Epigenetic reprogramming in hidradenitis suppurativa.

作者信息

Chhabra Gagan, Ahmad Nihal

机构信息

Department of Dermatology, University of Wisconsin, Madison, WI 53705.

William S. Middleton Veterans Affairs Medical Center, Madison, WI 53705.

出版信息

Proc Natl Acad Sci U S A. 2024 Jan 2;121(1):e2319797121. doi: 10.1073/pnas.2319797121. Epub 2023 Dec 26.

DOI:10.1073/pnas.2319797121

PMID:38147564

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10769847/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0dc3/10769847/baab2ee7b0a5/pnas.2319797121fig01.jpg

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本文引用的文献

Epigenetic switch reshapes epithelial progenitor cell signatures and drives inflammatory pathogenesis in hidradenitis suppurativa.

Proc Natl Acad Sci U S A. 2023 Dec 5;120(49):e2315096120. doi: 10.1073/pnas.2315096120. Epub 2023 Nov 27.

New insights into inflammatory memory of epidermal stem cells.

Front Immunol. 2023 May 31;14:1188559. doi: 10.3389/fimmu.2023.1188559. eCollection 2023.

Single-cell transcriptomics suggest distinct upstream drivers of IL-17A/F in hidradenitis versus psoriasis.

J Allergy Clin Immunol. 2023 Sep;152(3):656-666. doi: 10.1016/j.jaci.2023.05.012. Epub 2023 Jun 2.

Methods and applications for single-cell and spatial multi-omics.

Nat Rev Genet. 2023 Aug;24(8):494-515. doi: 10.1038/s41576-023-00580-2. Epub 2023 Mar 2.

Increased epigenetic age acceleration in the hidradenitis suppurativa skin.

Arch Dermatol Res. 2023 May;315(4):1037-1039. doi: 10.1007/s00403-022-02432-1. Epub 2022 Oct 29.

Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic Signaling.

Biomolecules. 2022 Sep 25;12(10):1371. doi: 10.3390/biom12101371.

Histopathology of Hidradenitis Suppurativa: A Systematic Review.

Dermatopathology (Basel). 2022 Jul 14;9(3):251-257. doi: 10.3390/dermatopathology9030029.

Gender differences in hidradenitis suppurativa characteristics: A retrospective cohort analysis.

Int J Womens Dermatol. 2021 Jul 17;7(5Part B):672-674. doi: 10.1016/j.ijwd.2021.07.003. eCollection 2021 Dec.

Increased Serum Levels of S100A4 and S100A15 in Individuals Suffering from Hidradenitis Suppurativa.

J Clin Med. 2021 Nov 15;10(22):5320. doi: 10.3390/jcm10225320.

Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa.

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