Mainga Tila, Schaap Ab, Scherer Nathaniel, Mactaggart Islay, Shanaube Kwame, Ayles Helen, Bond Virginia, Stewart Robert C
Zambart, School of Public Health, University of Zambia, Ridgeway, Zambia.
Department of Global Health and Development, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, UK.
Glob Ment Health (Camb). 2023 Nov 28;10:e89. doi: 10.1017/gmh.2023.83. eCollection 2023.
People with tuberculosis (TB) are susceptible to mental distress. Mental distress can be driven by biological and socio-economic factors including poverty. These factors can persist beyond TB treatment completion yet there is minimal evidence about the mental health of TB survivors. A cross-sectional TB prevalence survey of adults was conducted in an urban community in Zambia. Survey participants were administered the five-item Self Reporting Questionnaire (SRQ-5) mental health screening tool to measure mental distress. Associations between primary exposure (history of TB) and other co-variates with mental distress were investigated using logistic regression. Of 3,393 study participants, 120 were TB survivors (3.5%). The overall prevalence of mental distress (SRQ-5 ≥ 4) in the whole study population was 16.9% (95% CI 15.6%-18.1%). Previous TB history was not associated with mental distress (OR 1.20, 95% CI 0.75-1.92, -value 1.66). Mental distress was associated with being female (OR 1.23 95% CI 1.00-1.51), older age (OR 1.71 95% CI 1.09-2.68) and alcohol abuse (OR 1.81 95% CI 1.19-2.76). Our findings show no association between a previous TB history and mental distress. However, approximately one in six people in the study population screened positive for mental distress.
肺结核患者易出现精神困扰。精神困扰可能由包括贫困在内的生物和社会经济因素引发。这些因素在结核病治疗结束后仍可能持续存在,但关于结核病幸存者心理健康的证据却很少。在赞比亚的一个城市社区对成年人进行了一项横断面结核病患病率调查。对调查参与者使用了包含五个条目的自评问卷(SRQ-5)心理健康筛查工具来测量精神困扰。使用逻辑回归研究了主要暴露因素(结核病病史)和其他协变量与精神困扰之间的关联。在3393名研究参与者中,有120名是结核病幸存者(3.5%)。整个研究人群中精神困扰(SRQ-5≥4)的总体患病率为16.9%(95%置信区间15.6%-18.1%)。既往结核病病史与精神困扰无关(比值比1.20,95%置信区间0.75-1.92,P值1.66)。精神困扰与女性(比值比1.23,95%置信区间1.00-1.51)、年龄较大(比值比1.71,95%置信区间1.09-2.68)和酗酒(比值比1.81,95%置信区间1.19-2.76)有关。我们的研究结果表明,既往结核病病史与精神困扰之间没有关联。然而,研究人群中约六分之一的人精神困扰筛查呈阳性。