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[纤维蛋白鞘包裹的功能失调带隧道带涤纶套导管的血液透析患者的导管更换方法]

[Catheter Replacement Methods in Hemodialysis Patients With Dysfunctional Tunneled-Cuffed Catheters With Fibrin Sheaths].

作者信息

Jin Lizhu, Wang Hui, Cui Tianlei, Liao Ruoxi

机构信息

( 610041) Department of Nephrology, West China Hospital, Sichuan University, Chengdu 610041, China.

( 610014) Department of Nephrology, The Third People's Hospital of Chengdu, Chengdu 610014, China.

出版信息

Sichuan Da Xue Xue Bao Yi Xue Ban. 2023 Nov 20;54(6):1283-1287. doi: 10.12182/20231160201.

Abstract

OBJECTIVE

Tunneled-cuffed catheters (TCCs) are frequently used for establishing hemodialysis access for maintenance hemodialysis in older patients with exhausted resources of peripheral vessels. Fibrin sheath formation around the catheter is one of the most common complications of long-term use of indwelling catheter, which may cause the malfunction of the catheter. In this study, we intend to compare the prognosis of two catheter replacement methods, replacement and replacement through a fibrin sheath crevice, with both being assisted by balloon dilation, and to explore the optimal catheter replacement process.

METHODS

A retrospective study was conducted with 52 patients who underwent a replacement of their TCCs. Among them, 27 cases had their TCC replaced by the modified method of replacement through a fibrin sheath crevice and were referred to as the sheath crevice group, while 25 cases underwent catheter replacement and were referred to as the group. The primary outcome indicators included maximum blood flow in hemodialysis catheter and the urea clearance rate calculated by Kt/V values at the 1, 3, and 6-month follow-ups. The secondary outcomes included dialyzer alarms being set off and catheter-related infections during follow-up.

RESULTS

There was no significant difference between the general data of the two groups. There was no massive blood loss during the replacement procedure. Neither were there cardiac tamponade, catheter-associated infections, or other complications. Follow-ups were made 1, 3, and 6 months after the replacement procedure. The sheath crevice group had higher catheter blood flow and Kt/V values at the 6-month follow-up than the group did ([241.85±9.62] mL/min vs. [234.40±11.21] mL/min, =0.014 and 1.31±0.55 vs. 1.27±0.49, =0.005, respectively). During the follow-up process, access alarms were reported in 5 patients (three in the group and two in the sheath crevice group) during dialysis. No catheter-associated infection occurred in either group.

CONCLUSION

The catheter replacement method of balloon dilation-assisted catheter insertion through a fibrin sheath crevice is safe and effective, resulting in better long-term catheter blood flow compared with that of catheter replacement.

摘要

目的

隧道式带 cuff 导管(TCCs)常用于外周血管资源枯竭的老年患者建立维持性血液透析通路。导管周围纤维蛋白鞘形成是长期留置导管最常见的并发症之一,可能导致导管功能障碍。在本研究中,我们旨在比较两种在球囊扩张辅助下的导管置换方法,即置换法和经纤维蛋白鞘裂隙置换法的预后,并探索最佳的导管置换过程。

方法

对 52 例行 TCCs 置换的患者进行回顾性研究。其中,27 例采用改良的经纤维蛋白鞘裂隙置换法置换 TCCs,称为鞘裂隙组,25 例进行导管置换,称为置换组。主要结局指标包括血液透析导管的最大血流量以及在 1、3 和 6 个月随访时通过 Kt/V 值计算的尿素清除率。次要结局包括随访期间透析器报警及导管相关感染。

结果

两组一般资料无显著差异。置换过程中无大量失血。也未发生心脏压塞、导管相关感染或其他并发症。置换术后 1、3 和 6 个月进行随访。鞘裂隙组在 6 个月随访时的导管血流量和 Kt/V 值高于置换组(分别为[241.85±9.62]mL/min 对[234.40±11.21]mL/min,P = 0.014;1.31±0.55 对 1.27±0.49,P = 0.005)。随访过程中,透析期间有 5 例患者(置换组 3 例,鞘裂隙组 2 例)出现通路报警。两组均未发生导管相关感染。

结论

球囊扩张辅助经纤维蛋白鞘裂隙插入导管的置换方法安全有效,与导管置换相比,长期导管血流量更好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f44/10752794/b8e0a611728f/scdxxbyxb-54-6-1283-1.jpg

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