人类类原肠胚：胚胎学研究的一项重大进展。

Human peri-gastruloids: a significant advancement in embryology research.

作者信息

Yang Qin, Burstein Ezra, Jia Da

机构信息

Key Laboratory of Birth Defects and Related Diseases of Women and Children Department of Paediatrics West China Second University Hospital, State Key Laboratory of Biotherapy Sichuan University Chengdu China.

Department of Internal Medicine University of Texas Southwestern Medical Center Dallas Texas USA.

出版信息

MedComm (2020). 2023 Dec 30;5(1):e445. doi: 10.1002/mco2.445. eCollection 2024 Jan.

DOI:10.1002/mco2.445

PMID:38163088

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10757121/

Abstract

The peri-gastruloids comprise both embryonic (epiblast) and extraembryonic (hypoblast) tissues, faithfully mirroring crucial developmental events spanning from the immediate post-implantation phase to early organogenesis, encompassing the emergence of amniotic and yolk sac cavities, as well as the progression from bilaminar to trilaminar embryonic discs.

摘要

类原肠胚包含胚胎组织（上胚层）和胚外组织（下胚层），忠实地反映了从着床后即刻阶段到早期器官发生的关键发育事件，包括羊膜腔和卵黄囊腔的出现，以及从双胚层胚胎盘到三胚层胚胎盘的发育进程。