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隔离对 PTSD 症状和抑郁共病的影响:来自中国 PTRP-5-6 的证据。

The impact of isolation on comorbidity of PTSD symptoms and depression: evidence from PTRP-5-6 in China.

机构信息

Lab for Post-traumatic Stress Disorder, Faculty of Psychology and Mental Health, Naval Medical University, 800 Xiangyin Road, Shanghai, 200433, China.

The Emotion & Cognition Lab, Faculty of Psychology and Mental Health, Naval Medical University, Shanghai, 200433, China.

出版信息

BMC Public Health. 2024 Jan 2;24(1):21. doi: 10.1186/s12889-023-17450-5.

DOI:10.1186/s12889-023-17450-5
PMID:38166952
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10762958/
Abstract

BACKGROUND

The Omicron pandemic struck Shanghai, China, resulting in impairments of both physical and psychological health on those patients who were confirmed and transferred to the Fangcang shelters. The way of isolation led to high risk of posttraumatic stress symptoms (PTSS) and depressive symptoms among the patients in Fangcang shelters. We aim to estimate the prevalence and comorbidity of PTSS and depressive symptoms in patients from China's Fangcang shelters during the epidemic.

METHODS

Demographic information questionnaire, the posttraumatic stress disorder checklist for DSM-5 (PCL-5), and Patient Health Questionnaire (PHQ-9) were used in the study. The data were collected online via mobile phones during 10th April to 20th April, 2022, as part of our Psychological Trauma Recover Project-5-6 (PTRP-5-6), a longitudinal study focusing on individuals who have experienced trauma.

RESULTS

A total of 336 subjects were included in the analysis. The results revealed (1) the prevalence of depressive symptoms, and PTSS were 30.1% (cut-off = 10) and 6% (cut-off = 33); (2) Multiple logistic regression showed that female (OR = 3.04, p < 0.05), suffering from dyspnea (OR = 5.83, p < 0.05) or gastrointestinal symptoms (OR = 6.38, p < 0.05) were risk factors for PTSS; higher education level (OR = 3.27, p < 0.05) and suffering from dizziness or headache (OR = 2.46, p < 0.05) were risk factors for depressive symptoms; (3)Respectively, 85% of the patients who reported PTSS also experienced depressive symptoms, 16.8% of the patients who reported depressive symptoms presented PTSS.

CONCLUSION

In the context of COVID-19, the comorbidity rate of PTSS and depressive symptoms among patients in Fangcang shelters increased with the severity of depressive symptoms.

摘要

背景

奥密克戎疫情袭击中国上海,导致确诊并转入方仓庇护所的患者身心健康受损。这种隔离方式导致方仓庇护所患者发生创伤后应激症状(PTSS)和抑郁症状的风险较高。我们旨在评估疫情期间中国方仓庇护所患者 PTSS 和抑郁症状的患病率和共病率。

方法

采用人口统计学信息问卷、DSM-5 创伤后应激障碍检查表(PCL-5)和患者健康问卷(PHQ-9)进行研究。数据于 2022 年 4 月 10 日至 4 月 20 日期间通过手机在线收集,作为我们的心理创伤恢复项目-5-6(PTRP-5-6)的一部分,该纵向研究侧重于经历过创伤的个体。

结果

共纳入 336 名受试者进行分析。结果显示:(1)抑郁症状和 PTSS 的患病率分别为 30.1%(截断值=10)和 6%(截断值=33);(2)多因素逻辑回归显示,女性(OR=3.04,p<0.05)、呼吸困难(OR=5.83,p<0.05)或胃肠道症状(OR=6.38,p<0.05)是 PTSS 的危险因素;较高的教育水平(OR=3.27,p<0.05)和头晕或头痛(OR=2.46,p<0.05)是抑郁症状的危险因素;(3)分别有 85%报告 PTSS 的患者也经历了抑郁症状,16.8%报告抑郁症状的患者出现了 PTSS。

结论

在 COVID-19 背景下,方仓庇护所患者 PTSS 和抑郁症状的共病率随着抑郁症状的严重程度而增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcea/10762958/4b9e0e88a440/12889_2023_17450_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcea/10762958/4b9e0e88a440/12889_2023_17450_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcea/10762958/4b9e0e88a440/12889_2023_17450_Fig1_HTML.jpg

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