Tou Sio-Ian, Lin Cheng-Li, Huang Chia-Yu, Yen Hung-Rong
Department of Pediatrics, Chung Kang Branch, Cheng-Ching General Hospital, Taichung, Taiwan.
Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan.
J Multidiscip Healthc. 2023 Dec 29;16:4307-4320. doi: 10.2147/JMDH.S416892. eCollection 2023.
Coprescription means that patients use different prescription medications at the same time, which can lead to polypharmacy and subsequent complications. In Taiwan, prescriptions can be ordered by Western physicians, traditional Chinese physicians and dentists. It is essential to disclose the trends in coprescription to prevent possible polypharmacy among children.
We used the Longitudinal Health Insurance Database 2000 in Taiwan. Children <18 years old who had coprescription from 2002 to 2012 are included. The odds ratio and 95% confidence interval are estimated by a logistic regression model to evaluate the correlation between basic characteristics and coprescription.
A total of 44,801 children are included in the analysis. The numbers of children with coprescription and the numbers of coprescriptions ordered for children increased with calendar years. Children aged 3-5 year and 6-8 years constituted the majority of coprescriptions, while those aged <3 years constituted the minority of coprescriptions. Compared to those in the Western medication-alone group, aged 3-5 years and children who lived in central and southern Taiwan are more likely to have coprescription.
Coprescription among Taiwanese children is not uncommon. Healthcare providers, policymakers and parents should be aware of the real coprescription situation among the children.
联合处方是指患者同时使用不同的处方药,这可能导致多重用药及随后的并发症。在台湾,西医、中医和牙医均可开具处方。揭示联合处方的趋势对于预防儿童可能出现的多重用药至关重要。
我们使用了台湾2000年纵向健康保险数据库。纳入2002年至2012年期间有联合处方的18岁以下儿童。通过逻辑回归模型估计比值比和95%置信区间,以评估基本特征与联合处方之间的相关性。
共有44,801名儿童纳入分析。联合处方的儿童数量以及为儿童开具的联合处方数量随历年增加。3至5岁和6至8岁的儿童构成联合处方的大多数,而3岁以下儿童构成联合处方的少数。与仅使用西药组相比,3至5岁儿童以及居住在台湾中部和南部的儿童更有可能有联合处方。
台湾儿童联合处方并不罕见。医疗保健提供者、政策制定者和家长应了解儿童中联合处方的实际情况。