Xiang Yu, He Jinyue, Bai Ruonan, Gou Huorong, Luo Fei, Huang Xuequan, Zhang Zehua
Department of Orthopedics, Southwest Hospital, Army Medical University, Chongqing, China.
Department of Anesthesia, Southwest Hospital, Army Medical University, Chongqing, China.
Neurospine. 2023 Dec;20(4):1389-1398. doi: 10.14245/ns.2346820.410. Epub 2023 Dec 31.
To investigate the value of Hounsfield units (HUs) as an independent predictor of failed percutaneous drainage of spinal tuberculosis paraspinal abscess under computed tomography (CT) guidance.
A retrospective analysis was conducted on 61 patients who underwent CT-guided percutaneous drainage for spinal tuberculosis paraspinal abscess between October 2017 and October 2020. Preoperative CT scans were used to measure the HUs of the abscess. Patients were categorized into successful drainage (n = 49) and failed drainage (n = 12) groups. Statistical analysis involved independent sample t-tests and chi-square tests to compare between the 2 groups. Binary logistic regression was performed to identify independent predictive factors for drainage failure. Receiver operating characteristic (ROC) curves were employed to ascertain risk factor thresholds and diagnostic performance.
Among the patients, 49 experienced successful drainage while 12 faced drainage failure. The mean HUs of abscesses in the failed drainage group were significantly higher than those in the successful drainage group (p < 0.001). ROC analysis revealed an area under the curve of 0.897 (95% confidence interval, 0.808-0.986) for predicting drainage failure based on HUs. The optimal HU cutoff value for predicting drainage failure was 22.3, with a sensitivity of 91.7% and specificity of 69.4%.
HUs are an independent predictor of failed percutaneous drainage of spinal tuberculosis paraspinal abscess under CT guidance. The HU value of 22.3 can be used as an initial screening threshold for predicting the success or failure of drainage.
探讨在计算机断层扫描(CT)引导下,亨氏单位(HUs)作为脊柱结核椎旁脓肿经皮引流失败的独立预测指标的价值。
对2017年10月至2020年10月间61例行CT引导下脊柱结核椎旁脓肿经皮引流的患者进行回顾性分析。术前CT扫描用于测量脓肿的亨氏单位。将患者分为引流成功组(n = 49)和引流失败组(n = 12)。采用独立样本t检验和卡方检验进行两组间比较。进行二元逻辑回归以确定引流失败的独立预测因素。采用受试者工作特征(ROC)曲线确定危险因素阈值和诊断性能。
患者中,49例引流成功,12例引流失败。引流失败组脓肿的平均亨氏单位显著高于引流成功组(p < 0.001)。ROC分析显示,基于亨氏单位预测引流失败的曲线下面积为0.897(95%置信区间,0.808 - 0.986)。预测引流失败的最佳亨氏单位临界值为22.3,灵敏度为91.7%,特异度为69.4%。
在CT引导下,亨氏单位是脊柱结核椎旁脓肿经皮引流失败的独立预测指标。22.3的亨氏单位值可作为预测引流成败的初始筛查阈值。