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儿童多系统炎症综合征(MIS-C),一名幼儿最初表现为发热和脓尿。

Multisystem inflammatory syndrome in children (MIS-C) of a toddler initially presenting with fever and pyuria.

机构信息

Department of Family Medicine, National University Health System, Singapore

Department of Family Medicine, National University Health System, Singapore.

出版信息

BMJ Case Rep. 2024 Jan 3;17(1):e253756. doi: 10.1136/bcr-2022-253756.

Abstract

We report a case of multisystem inflammatory syndrome in children (MIS-C) in an East Asian toddler. He presented with a 2-day history of fever and pyuria, 5 weeks before that he had recovered from COVID-19. He was initially treated as urinary tract infection. On day 5 of fever, he was noted to have bilateral non-suppurative limbus-sparing conjunctivitis, red and cracked lips and erythematous extremities. Investigations showed raised inflammatory markers (C-reactive protein and erythrocyte sedimentation rate), thrombocytopenia and a markedly elevated NT-proBNP. He received prompt and appropriate treatment inpatient; however, he still had mild coronary abnormalities at 9 months postdischarge. The aim of this paper is to describe the initial presentation and progress of a case of MIS-C. The unique features of this case are his initial presentation of pyuria and notably, his demography (young age, East Asian) which is more typical of Kawasaki disease than MIS-C.

摘要

我们报告了一例东亚幼儿的儿童多系统炎症综合征(MIS-C)。他有发热和脓尿病史 2 天,在这之前 5 周曾从 COVID-19 中康复。他最初被诊断为尿路感染。发热第 5 天,他出现双侧非化脓性角膜缘保留性结膜炎、唇红干裂和四肢红斑。检查显示炎症标志物(C 反应蛋白和红细胞沉降率)升高、血小板减少和明显升高的 NT-proBNP。他在住院期间得到了及时和适当的治疗;然而,出院后 9 个月时他仍有轻度冠状动脉异常。本文旨在描述一例 MIS-C 的初始表现和进展。该病例的独特之处在于他最初表现为脓尿,且他的年龄(幼儿)和人种(东亚)更符合川崎病,而非 MIS-C。

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本文引用的文献

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Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2: a case report.
Hong Kong Med J. 2022 Feb;28(1):76-78. doi: 10.12809/hkmj219689. Epub 2022 Feb 14.
3
Multisystem inflammatory syndrome in children and Kawasaki disease: a critical comparison.
Nat Rev Rheumatol. 2021 Dec;17(12):731-748. doi: 10.1038/s41584-021-00709-9. Epub 2021 Oct 29.
5
Multisystem Inflammatory Syndrome in U.S. Children and Adolescents.
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6
Hyperinflammatory shock in children during COVID-19 pandemic.
Lancet. 2020 May 23;395(10237):1607-1608. doi: 10.1016/S0140-6736(20)31094-1. Epub 2020 May 7.

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