Department of Family Medicine, National University Health System, Singapore
Department of Family Medicine, National University Health System, Singapore.
BMJ Case Rep. 2024 Jan 3;17(1):e253756. doi: 10.1136/bcr-2022-253756.
We report a case of multisystem inflammatory syndrome in children (MIS-C) in an East Asian toddler. He presented with a 2-day history of fever and pyuria, 5 weeks before that he had recovered from COVID-19. He was initially treated as urinary tract infection. On day 5 of fever, he was noted to have bilateral non-suppurative limbus-sparing conjunctivitis, red and cracked lips and erythematous extremities. Investigations showed raised inflammatory markers (C-reactive protein and erythrocyte sedimentation rate), thrombocytopenia and a markedly elevated NT-proBNP. He received prompt and appropriate treatment inpatient; however, he still had mild coronary abnormalities at 9 months postdischarge. The aim of this paper is to describe the initial presentation and progress of a case of MIS-C. The unique features of this case are his initial presentation of pyuria and notably, his demography (young age, East Asian) which is more typical of Kawasaki disease than MIS-C.
我们报告了一例东亚幼儿的儿童多系统炎症综合征(MIS-C)。他有发热和脓尿病史 2 天,在这之前 5 周曾从 COVID-19 中康复。他最初被诊断为尿路感染。发热第 5 天,他出现双侧非化脓性角膜缘保留性结膜炎、唇红干裂和四肢红斑。检查显示炎症标志物(C 反应蛋白和红细胞沉降率)升高、血小板减少和明显升高的 NT-proBNP。他在住院期间得到了及时和适当的治疗;然而,出院后 9 个月时他仍有轻度冠状动脉异常。本文旨在描述一例 MIS-C 的初始表现和进展。该病例的独特之处在于他最初表现为脓尿,且他的年龄(幼儿)和人种(东亚)更符合川崎病,而非 MIS-C。