Roguski Amber, Ritter Philipp, Smith Daniel J
Division of Psychiatry, University of Edinburgh, UK; and Centre for Clinical Brain Sciences, University of Edinburgh, UK.
Clinic for Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technical University of Dresden, Germany.
Br J Psychiatry. 2024 May;224(5):143-146. doi: 10.1192/bjp.2023.150.
Circadian dysfunction is a core feature of bipolar disorder and may be due, at least in part, to abnormalities of non-visual photoreception. We critically review the evidence for light hypersensitivity in bipolar disorder and discuss how this may shape future research and clinical innovation, with a focus on a possible novel mechanism of action for lithium.
昼夜节律功能障碍是双相情感障碍的核心特征,至少部分原因可能是非视觉光感受器异常。我们严格审查了双相情感障碍中光过敏的证据,并讨论了这可能如何塑造未来的研究和临床创新,重点是锂盐可能的新作用机制。