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Legumain Regulates Regulatory T Cells in Hypertension.

作者信息

Alexander Matthew R, Harrison David G

机构信息

Department of Medicine, Division of Clinical Pharmacology, and Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN. Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN. Vanderbilt Institute for Infection, Immunology, and Inflammation, Nashville, TN.

出版信息

Circ Res. 2024 Jan 5;134(1):30-32. doi: 10.1161/CIRCRESAHA.123.324010. Epub 2024 Jan 4.

Abstract
摘要

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本文引用的文献

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CD4+ T-Cell Legumain Deficiency Attenuates Hypertensive Damage via Preservation of TRAF6.
Circ Res. 2024 Jan 5;134(1):9-29. doi: 10.1161/CIRCRESAHA.123.322835. Epub 2023 Dec 4.
2
Hypertension-Driven Regulatory T-Cell Perturbations Accelerate Myocardial Ischemia-Reperfusion Injury.
Hypertension. 2023 Oct;80(10):2046-2058. doi: 10.1161/HYPERTENSIONAHA.123.20481. Epub 2023 Aug 24.
3
Immune Profiling Reveals Decreases in Circulating Regulatory and Exhausted T Cells in Human Hypertension.
JACC Basic Transl Sci. 2023 Jan 4;8(3):319-336. doi: 10.1016/j.jacbts.2022.09.007. eCollection 2023 Mar.
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The Mammalian Cysteine Protease Legumain in Health and Disease.
Int J Mol Sci. 2022 Dec 15;23(24):15983. doi: 10.3390/ijms232415983.
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Hypertension: Do Inflammation and Immunity Hold the Key to Solving this Epidemic?
Circ Res. 2021 Apr 2;128(7):908-933. doi: 10.1161/CIRCRESAHA.121.318052. Epub 2021 Apr 1.
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Asparaginyl endopeptidase may promote liver sinusoidal endothelial cell angiogenesis via PI3K/Akt pathway.
Rev Esp Enferm Dig. 2019 Mar;111(3):214-222. doi: 10.17235/reed.2018.5709/2018.
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Asparaginyl Endopeptidase (Legumain) Supports Human Th1 Induction via Cathepsin L-Mediated Intracellular C3 Activation.
Front Immunol. 2018 Oct 24;9:2449. doi: 10.3389/fimmu.2018.02449. eCollection 2018.

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