Bouvet Lionel, Fabre Juliette, Roussin Charlotte, Nadal Camille, Dezavelle Sylvain, Vial Florence, Le Gouez Agnès, Soued Mickael, Keita Hawa, Zein Waed, Desgranges François-Pierrick, Thuet Vincent, Boucekine Mohamed, Duclos Gary, Leone Marc, Zieleskiewicz Laurent
Department of Anaesthesiology and Intensive Care, Hospices Civils de Lyon, Femme Mère Enfant Hospital, Bron, France; Research Unit APCSe VetAgro Sup UP 2021.A101 - University of Lyon, Université Claude Bernard Lyon 1, Villeurbanne, France.
Department of Anaesthesiology and Intensive Care, Hospices Civils de Lyon, Femme Mère Enfant Hospital, Bron, France.
Br J Anaesth. 2024 Mar;132(3):553-561. doi: 10.1016/j.bja.2023.11.043. Epub 2024 Jan 4.
This multicentre prospective observational study sought to determine the prevalence and the factors associated with high-risk gastric contents in women admitted to the maternity unit for childbirth, and to identify the clinical situations in which ultrasound assessment of gastric contents would be most helpful (i.e. when the prevalence of high-risk gastric contents is close to 50%).
Ultrasound assessments of gastric contents were performed within the first hour after admission to the maternity unit. The prevalence of high-risk gastric contents was calculated and variables associated with high-risk gastric contents were identified using logistic regression analyses.
A total of 1003 parturients were analysed. The prevalence of high-risk gastric contents was 70% (379/544; 95% confidence interval: 66-74%) in women admitted in spontaneous labour and 65% (646/1003; 95% confidence interval: 61-67%) in the whole cohort. Lower gestational age, increased fasting duration for solids, and elective Caesarean delivery were independently associated with reduced likelihood of high-risk gastric contents. In women admitted in spontaneous labour and in the whole cohort, the prevalence of high-risk gastric contents ranged from 85% to 86% for fasting duration for solids <6 h, 63%-68% for fasting 6-8 h, 54%-55% for fasting 8-12 h, and 47%-51% for fasting ≥12 h.
Around two-thirds of parturients had high-risk gastric contents within the first hour after admission to the maternity unit. Our results suggest that gastric emptying for solids continues in labouring women, and that gastric ultrasound would be most helpful when fasting duration is ≥8 h.
这项多中心前瞻性观察性研究旨在确定入住产科病房分娩的女性中高危胃内容物的患病率及其相关因素,并确定超声评估胃内容物最有帮助的临床情况(即高危胃内容物患病率接近50%时)。
在入住产科病房后的第一小时内对胃内容物进行超声评估。计算高危胃内容物的患病率,并使用逻辑回归分析确定与高危胃内容物相关的变量。
共分析了1003名产妇。自然分娩入院的女性中高危胃内容物的患病率为70%(379/544;95%置信区间:66-74%),整个队列中的患病率为65%(646/1003;95%置信区间:61-67%)。较低的孕周、固体禁食时间延长和择期剖宫产与高危胃内容物的可能性降低独立相关。在自然分娩入院的女性和整个队列中,固体禁食时间<6小时时高危胃内容物的患病率为85%至86%,禁食6-8小时为63%-68%,禁食8-12小时为54%-55%,禁食≥12小时为47%-51%。
约三分之二的产妇在入住产科病房后的第一小时内有高危胃内容物。我们的结果表明,分娩女性的固体胃排空仍在继续,并且当禁食时间≥8小时时,胃超声最有帮助。