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甲状腺功能紊乱是否是休止期脱发的常见病因?一项回顾性研究。

Is thyroid dysfunction a common cause of telogen effluvium?: A retrospective study.

机构信息

Dermatology Unit, Department of Internal Medicine, College of Medicine. Prince Sattam Bin Abdulaziz University, AL-Kharj, Saudi Arabia.

Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, AL-Kharj, Saudi Arabia.

出版信息

Medicine (Baltimore). 2024 Jan 5;103(1):e36803. doi: 10.1097/MD.0000000000036803.

Abstract

Telogen effluvium (TE) is a common cause of hair loss characterized by excessive resting hair shedding. Thyroid dysfunction is one of the possible causes of TE. On the other hand, the link between thyroid disorder and TE is still being debated. The aim of this retrospective is to investigate the link between thyroid dysfunction and TE. This retrospective study included 500 female patients with TE who had thyroid function testing between January 2012 and December 2022. Patients were eligible if they had a confirmed TE diagnosis and thyroid function tests within 3 months of being diagnosed with TE. The thyroid function of the participants was classified as euthyroid, hypothyroidism, or hyperthyroidism. The severity of hair loss was determined using the severity of alopecia tool (SALT) score. The study included 500 TE females, 248 of whom were euthyroid, 150 had hypothyroidism, and 102 had hyperthyroidism. The hypothyroid group had a significantly higher mean SALT score than the other 2 groups. Furthermore, patients in the hypothyroid group had a higher proportion of severe hair loss. The mean SALT score did not differ significantly between groups with normal thyroid function and those with hyperthyroidism. A common cause of TE is thyroid dysfunction, particularly hypothyroidism. Patients with hypothyroidism have more severe hair loss than those with normal thyroid function or hyperthyroidism. To effectively identify and manage such cases, thyroid function testing should be included in the diagnostic workup of patients with TE.

摘要

休止期脱发(TE)是一种常见的脱发症,其特征是休止期毛发过度脱落。甲状腺功能障碍是 TE 的可能原因之一。另一方面,甲状腺疾病与 TE 之间的联系仍存在争议。本回顾性研究旨在探讨甲状腺功能障碍与 TE 之间的联系。这项回顾性研究纳入了 500 名患有 TE 的女性患者,她们在 2012 年 1 月至 2022 年 12 月期间进行了甲状腺功能检查。如果患者确诊为 TE,且在诊断 TE 后 3 个月内进行了甲状腺功能检查,则符合入选条件。将参与者的甲状腺功能分为甲状腺功能正常、甲状腺功能减退和甲状腺功能亢进。使用脱发严重程度工具(SALT)评分来确定脱发的严重程度。该研究纳入了 500 名 TE 女性患者,其中 248 名甲状腺功能正常,150 名甲状腺功能减退,102 名甲状腺功能亢进。甲状腺功能减退组的平均 SALT 评分明显高于其他两组。此外,甲状腺功能减退组中严重脱发的患者比例更高。甲状腺功能正常组和甲状腺功能亢进组之间的平均 SALT 评分无显著差异。甲状腺功能障碍是 TE 的常见病因,尤其是甲状腺功能减退。甲状腺功能减退症患者的脱发比甲状腺功能正常或甲状腺功能亢进症患者更严重。为了有效识别和管理此类病例,应在 TE 患者的诊断工作中包括甲状腺功能检查。

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