Bacchi Pedro, Suen Paulo, Fatori Daniel, Razza Lais B, Afonso Leonardo, Klein Izio, Cavendish Beatriz, Moreno Marina L, Santos Itamar S, Benseñor Isabela, Lotufo Paulo, Brunoni André R
Laboratório de Neurociências (LIM-27), Departamento de Psiquiatria, Instituto de Psiquiatria, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, Brazil.
Laboratório de Neurociências (LIM-27), Departamento de Psiquiatria, Instituto de Psiquiatria, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, Brazil. Faculdade de Medicina, USP, São Paulo, SP, Brazil.
Trends Psychiatry Psychother. 2024;46:e20230701. doi: 10.47626/2237-6089-2023-0701. Epub 2024 Jan 6.
This study investigated the incidence of suicidal ideation and its associated risk factors in the state of São Paulo in the Brazilian Longitudinal Study of Adult Health (Estudo Longitudinal de Saúde do Adulto [ELSA-Brasil]) cohort during the coronavirus disease 2019 (COVID-19) pandemic.
In a pre-pandemic ELSA-Brasil onsite assessment in 2016-2018 (wave 3) and a pandemic online assessment in May-July 2020 (wave COVID), we assessed suicidal ideation using the Clinical Interview Schedule-Revised (CIS-R). Single and multi predictor logistic regressions were performed using sociodemographic characteristics, household financial impact during the pandemic, presence of previous chronic diseases, alcohol abuse, adverse childhood experiences (ACE), living alone, and previous common mental disorders (CMD) as predictors. Incidence of suicidal ideation was used as outcome.
Out of 4,191 participants in wave 3, 2,117 (50.5%) also answered the COVID wave. There was a threefold increase in suicide ideation, from 34 (1.8%) to 104 (5.6%) participants. In multiple predictor models, we found that previous CMD (odds ratio [OR] 7.17; 95% confidence interval [95%CI] 4.43 - 11.58) and ACE (OR 1.72; 95%CI 1.09 - 2.72) increased the odds of incident suicidal ideation. The sociodemographic predictors female sex, younger age, and low income were significant risk factors in the single predictor models only.
These findings underscore the importance of monitoring and supporting individuals who suffered ACE and have a history of mental health disorders. This is especially critical in times of heightened societal stress, such as the COVID-19 pandemic.
本研究在巴西成人健康纵向研究(ELSA - Brasil)队列中,调查了2019年冠状病毒病(COVID - 19)大流行期间圣保罗州自杀意念的发生率及其相关风险因素。
在2016 - 2018年(第3波)进行的大流行前ELSA - Brasil现场评估以及2020年5 - 7月进行的大流行期间在线评估(COVID波)中,我们使用修订版临床访谈时间表(CIS - R)评估自杀意念。以社会人口学特征、大流行期间家庭经济影响、既往慢性病的存在、酒精滥用、童年不良经历(ACE)、独居以及既往常见精神障碍(CMD)作为预测因素,进行单因素和多因素预测逻辑回归分析。自杀意念的发生率作为结果。
在第3波的4191名参与者中,有2117名(50.5%)也回答了COVID波的调查。自杀意念增加了两倍,从34名(1.8%)参与者增至104名(5.6%)。在多因素预测模型中,我们发现既往CMD(比值比[OR] 7.17;95%置信区间[95%CI] 4.43 - 11.58)和ACE(OR 1.72;95%CI 1.09 - 2.72)增加了发生自杀意念的几率。社会人口学预测因素中,女性、较年轻年龄和低收入仅在单因素预测模型中是显著风险因素。
这些发现强调了监测和支持遭受过ACE且有精神健康障碍病史者的重要性。在社会压力加剧时期,如COVID - 19大流行期间,这一点尤为关键。