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经软骨膜入路改良的胸腹神经阻滞对腹腔镜胆囊切除术患者术后疼痛和镇痛药物消耗的影响。

Effects of Modified Thoracoabdominal Nerve Block Through Perichondrial Approach on Postoperative Pain and Analgaesic Consumption in Patients Undergoing Laparoscopic Cholecystectomy.

机构信息

Department of Anaesthesiology and Reanimation, School of Medicine, Sivas Cumhuriyet University, Sivas, Turkiye.

出版信息

J Coll Physicians Surg Pak. 2024 Jan;34(1):5-10. doi: 10.29271/jcpsp.2024.01.05.

Abstract

OBJECTIVE

To investigate postoperative analgaesic efficacy of modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) and its effect on opioid consumption in patients undergoing laparoscopic cholecystectomy (LC) surgery.

STUDY DESIGN

Randomised, controlled trial. Place and Duration of the Study: Department of Anaesthesiology and Reanimation, Sivas Cumhuriyet University, Sivas, Turkiye, from April to May 2023.

METHODOLOGY

The study was conducted in two randomised groups: M-TAPA (n = 21) and control group (CG) (no block) (n = 21). All patients had standard general anaesthesia. M-TAPA patients had bilateral M-TAPA block with 0.25% bupivacaine (total volume, 40 ml) at the end of the surgery. In contrast, CG patients had only tramadol for postoperative pain. A numerical rating scale (NRS) and visual analogue scale (VAS) were used for postoperative pain assessment. Total tramadol consumption was calculated.

RESULTS

M-TAPA's NRS and VAS scores were lower in postoperative 24 hours (p<0.05). Total tramadol consumption was 116.67 ± 32.91 mg in CG and 35.71 ± 39.19 mg in M-TAPA (p<0.001).

CONCLUSION

Bilateral M-TAPA block for postoperative pain control after LC surgery provided effective analgaesia for up to 24 hours and reduced total opioid consumption. Although the M-TAPA block is a novel approach, it will be a part of multimodal analgaesia for routine postoperative pain management in abdominal surgeries. However, more studies with higher numbers of patients will be needed.

KEY WORDS

Analgaesia, Bupivacaine, Laparoscopic cholecystectomy, Nerve block, Pain management.

摘要

目的

探讨经软骨膜入路改良胸腹神经阻滞(M-TAPA)在腹腔镜胆囊切除术(LC)患者中的术后镇痛效果及其对阿片类药物消耗的影响。

研究设计

随机对照试验。研究地点和时间:土耳其锡瓦斯共和国大学麻醉与复苏科,2023 年 4 月至 5 月。

方法

研究分为两组:M-TAPA 组(n=21)和对照组(CG)(无阻滞)(n=21)。所有患者均接受标准全身麻醉。M-TAPA 组患者在手术结束时接受双侧 M-TAPA 阻滞,用 0.25%布比卡因(总容量 40ml)。相比之下,CG 组患者仅在术后使用曲马多止痛。采用数字评分量表(NRS)和视觉模拟评分量表(VAS)评估术后疼痛。计算总曲马多消耗量。

结果

M-TAPA 组术后 24 小时 NRS 和 VAS 评分较低(p<0.05)。CG 组总曲马多消耗量为 116.67±32.91mg,M-TAPA 组为 35.71±39.19mg(p<0.001)。

结论

LC 手术后双侧 M-TAPA 阻滞可有效控制术后疼痛长达 24 小时,并减少阿片类药物总消耗量。虽然 M-TAPA 阻滞是一种新的方法,但它将成为腹部手术常规术后疼痛管理中多模式镇痛的一部分。然而,需要更多患者的更大规模研究。

关键词

镇痛,布比卡因,腹腔镜胆囊切除术,神经阻滞,疼痛管理。

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