Roohafza Hamidreza, Shojaei Yasaman, Azizian Sana, Zamani Zeinab, Shafiei Mohammadreza, Masoumi Gholamreza, Sadeghi Masoumeh
Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2023 Nov 29;12:251. doi: 10.4103/abr.abr_155_22. eCollection 2023.
Because of the important role of adhering to treatment to reduce major adverse cardiovascular events and mortality, studying the factors affecting treatment adherence (TA) is warranted. This study aimed to identify the impact of psychosomatic factors on adhering to treatment among patients with acute myocardial infarction.
This is a cohort study as a part of the Isfahan ST-segment-elevated Myocardial Infarction Cohort Study. Psychosomatic factors such as health anxiety, illness denial, irritable mood, and demoralization were assessed among 867 patients at the first visit. The patients were followed for 2 years; TA and major adverse cardiovascular events were checked annually in survivors.
The results from binary logistic regression applied to find the association between TA and psychosomatic factors showed that the patients with health anxiety, irritable mood, and demoralization were significantly poor adherent to treatment (odds ratio [95% confidence interval]: 1.39 [1.02, 2.73], 1.51 [1.02, 2.37], and 1.66 [1.02, 2.91]), respectively. The associations remained the same when adjusted for various potential confounders.
Psychosomatic factors played an essential role in adhering to treatment among patients with acute myocardial infarction. As a result, appropriate psychological interventions may help the patients adhere to their treatment better.
由于坚持治疗对于降低主要心血管不良事件和死亡率具有重要作用,因此有必要研究影响治疗依从性(TA)的因素。本研究旨在确定心身因素对急性心肌梗死患者治疗依从性的影响。
这是一项队列研究,是伊斯法罕ST段抬高型心肌梗死队列研究的一部分。在867例患者首次就诊时评估其健康焦虑、疾病否认、易怒情绪和士气低落等心身因素。对患者进行2年随访;每年对幸存者检查TA和主要心血管不良事件。
应用二元逻辑回归分析TA与心身因素之间关联的结果显示,健康焦虑、易怒情绪和士气低落的患者治疗依从性显著较差(比值比[95%置信区间]:分别为1.39[1.02,2.73]、1.51[1.02,2.37]和1.66[1.02,2.91])。在对各种潜在混杂因素进行调整后,这些关联仍然相同。
心身因素在急性心肌梗死患者的治疗依从性中起着至关重要的作用。因此,适当的心理干预可能有助于患者更好地坚持治疗。