Ozturk Nazli Begum, Dinc Ece Janet, Swami Abhishek, Gurakar Ahmet
Department of Internal Medicine, Beaumont Hospital, Royal Oak, MI 48073, USA.
School of Medicine, Baskent University, 06790 Ankara, Turkey.
J Clin Med. 2023 Dec 29;13(1):199. doi: 10.3390/jcm13010199.
Acute kidney injury (AKI) is common in hospitalized patients with cirrhosis. Hepatorenal syndrome (HRS) is a type of AKI known as HRS-AKI. It is a severe complication of cirrhosis with high morbidity and mortality. While certain vasoconstrictor medications have been shown to improve HRS-AKI, no clear transplant-free survival benefit has been reported with medical therapies. Patients with HRS-AKI should be considered for urgent liver transplantation evaluation. In this review, we discuss the most recent updates on the definition, diagnosis, and management of AKI in cirrhosis, with special a emphasis on HRS.
急性肾损伤（AKI）在肝硬化住院患者中很常见。肝肾综合征（HRS）是一种被称为HRS-AKI的AKI类型。它是肝硬化的一种严重并发症，发病率和死亡率都很高。虽然某些血管收缩剂药物已被证明可改善HRS-AKI，但医学治疗并未报告有明确的无移植生存获益。HRS-AKI患者应考虑进行紧急肝移植评估。在本综述中，我们讨论了肝硬化中AKI的定义、诊断和管理的最新进展，特别强调了HRS。
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