Özveren Bora, Karşıyakalı Nejdet, Türkeri Levent
Department of Urology, School of Medicine, Acıbadem Mehmet Ali Aydınlar University, Istanbul, Turkey.
Arab J Urol. 2023 Jun 10;22(1):31-38. doi: 10.1080/2090598X.2023.2222262. eCollection 2024.
To assess the incidence, risk factors, and timing of specific causes of reoperations following PVP.
A retrospective analysis of data on men who underwent GreenLight PVP between 2004 and 2019 in a single center and required surgical intervention for bladder neck contracture (BNC), urethral stricture (US), or persistent/recurrent prostate adenoma.
The overall rate of reoperations was 13.8% during a 61-month median follow-up of 377 patients. Reoperations were due to BNC, US, and adenoma in 7.7%, 5.6%, and 4.8% of cases, respectively. The median interval until reoperation for US (11 months) was significantly shorter. None of the risk factors had any relevance to US. In patients who underwent reoperation for BNC, lasing time and energy were significantly lower, and the prostate volume was smaller; however, the multivariate analysis only identified shorter lasing time as a predictor. In patients who had reoperation for persistent/recurrent adenoma, the PSA was increased, while the prostate volume was non-significantly high, and performance by less-experienced surgeons was associated with a higher rate of reoperations ( < 0.05). A longer lasing time predicted an increased risk of reoperation for adenoma in multivariate analysis.
An unselective utilization of PVP may result in a relatively high rate of reoperations. The correlation of BNC with shorter lasing time may imply a higher risk after PVP of smaller prostates. A longer lasing time predicts an increased risk of reoperation due to persistent/recurrent adenoma, which may be related to higher prostate volumes and inefficient PVP by less-experienced surgeons.
评估经尿道前列腺汽化术(PVP)后再次手术的特定原因的发生率、危险因素及时间。
对2004年至2019年在单一中心接受GreenLight PVP且因膀胱颈挛缩(BNC)、尿道狭窄(US)或持续性/复发性前列腺腺瘤而需要手术干预的男性患者的数据进行回顾性分析。
在377例患者的61个月中位随访期间,再次手术的总体发生率为13.8%。再次手术分别由BNC、US和腺瘤引起的病例占7.7%、5.6%和4.8%。US再次手术的中位间隔时间(11个月)明显更短。没有任何危险因素与US相关。在因BNC接受再次手术的患者中,激光照射时间和能量明显更低,前列腺体积更小;然而,多因素分析仅确定较短的激光照射时间为预测因素。在因持续性/复发性腺瘤接受再次手术的患者中,前列腺特异性抗原(PSA)升高,而前列腺体积虽无显著升高,但经验较少的外科医生进行手术与更高的再次手术率相关(P<0.05)。多因素分析中,较长的激光照射时间预示着腺瘤再次手术风险增加。
PVP的无选择性应用可能导致相对较高的再次手术率。BNC与较短激光照射时间的相关性可能意味着较小前列腺PVP后风险更高。较长的激光照射时间预示着因持续性/复发性腺瘤导致再次手术的风险增加,这可能与更大的前列腺体积以及经验较少的外科医生进行PVP效率低下有关。