Three dimensional study for entropy optimization in nanofluid flow through a compliant curved duct: A drug delivery and therapy application.

This research explores the three-dimensional characteristics of nanofluid dynamics within curved ducts, in contrast to earlier studies that mainly focus on two-dimensional flow. By using this ground-breaking method, we can capture a more accurate depiction of fluid behavior that complies with the intricate duct design. In this study, we investigate the three dimensional flow and entropic analysis of peristaltic nanofluid flows in a flexible curved duct, comparing the effects of silver and copper nanoparticles. To obtain accurate results, we assume physical constraints such as long wavelength and low Reynolds number and used a perturbation technique through NDSolve commands for finding exact solutions of the obtained differential equations. A comprehensive error analysis is provided through residual error table and figures to estimate a suitable range of the physical factors. Our findings indicate that the velocity of the nanofluid is directly proportional to the elasticity of the walls, while the mass per unit volume inversely affects velocity. We show that reducing the aspect ratio of the duct rectangular section can decrease entropy generation by raising magnitudes of damping force exerted by to the flexible walls of the enclosure. Additionally, using a larger height of the channel than the breadth can reduce stream boluses. The practical implications of this study extend beyond turbines and endoscopy to biomedical processes such as drug delivery and microfluidic systems.