Wang Cheng-Hui, Zhang Xiao-Wen, Chen Dan-Tong, Li Yuan-Xia, Huang Ying, Xiao Xin
Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Institute of Applied Chemistry, Guizhou University, Guiyang 550025, China.
Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Institute of Applied Chemistry, Guizhou University, Guiyang 550025, China.
Spectrochim Acta A Mol Biomol Spectrosc. 2024 Apr 5;310:123845. doi: 10.1016/j.saa.2024.123845. Epub 2024 Jan 5.
A supramolecular fluorescence probe has been developed using a symmetrical tetramethyl cucurbit[6]uril (TMeQ[6]) and a styryl derivative (SPy) with a host-guest ratio of 2:1. The introduction of paraquat (PQ) competes with SPy for the TMeQ[6] cavity, resulting in fluorescent quenching. The addition of 17 common herbicides and ions had negligible effects on the fluorescence quenching, indicating that the 2TMeQ[6]/SPy complex exhibits excellent selectivity in detecting PQ. The detection limit was found to be 4.62 × 10 M. More importantly, the probe was engineered to detect paraquat in river water by examining post-treatment samples and noting alterations in fluorescence color. The red to blue (R/B) intensity ratio is subsequently calculated to ascertain the PQ concentration. Experimental trials conducted on river water samples yielded recovery rates between 98.21 % and 108 %, with a relative standard deviation of less than 5 %. By pairing this with a smartphone-based colorimetric analysis application, we can facilitate portable PQ detection, enabling efficient and convenient monitoring across various locations.
一种超分子荧光探针已被开发出来，它使用了对称的四甲基葫芦[6]脲（TMeQ[6]）和一种苯乙烯基衍生物（SPy），主客体比例为2:1。百草枯（PQ）的引入与SPy竞争TMeQ[6]的空腔，导致荧光猝灭。添加17种常见除草剂和离子对荧光猝灭的影响可忽略不计，这表明2TMeQ[6]/SPy复合物在检测PQ时表现出优异的选择性。检测限为4.62×10⁻⁶ M。更重要的是，该探针经过设计，通过检测处理后的样品并记录荧光颜色的变化来检测河水中的百草枯。随后计算红/蓝（R/B）强度比以确定PQ浓度。对河水样品进行的实验试验回收率在98.21%至108%之间，相对标准偏差小于5%。通过将其与基于智能手机的比色分析应用程序相结合，我们可以实现便携式PQ检测，从而在各个地点进行高效便捷的监测。
