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后路Stoppa 入路髋臼骨折手术中腰方肌阻滞与髂筋膜间隙阻滞的对比:一项双盲、随机、非劣效性试验。

Quadratus Lumborum Block versus Fascia Iliaca Compartment Block for Acetabular Fracture Surgery by Stoppa Method: A Double-Blind, Randomized, Noninferiority Trial.

机构信息

Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Department of Anesthesiology and Pain Medicine, Kerman University of Medical Sciences, Kerman, Iran.

出版信息

Pain Res Manag. 2024 Jan 5;2024:3720344. doi: 10.1155/2024/3720344. eCollection 2024.

Abstract

BACKGROUND

Acetabular fracture surgeries are frequently accompanied by protracted and severe perioperative pain, and there is no consensus on optimal pain relief management.

AIM

This study aimed at comparing the analgesic efficacy of fascia iliaca compartment block (FICB) and quadratus lumborum block (QLB) in patients with acetabular fractures undergoing surgery using the Stoppa method.

METHODS

In this double-blind, randomized, noninferiority clinical trial, adult patients undergoing spinal anesthesia for acetabular fracture surgery, in Imam Hossein Hospital, Tehran, Iran (IRCT20191114045435N1), were randomly divided into two groups: FICB ( = 22) and QLB ( = 24). The visual analog scale (VAS) was used to assess the pain intensity at different times for all participants. In addition, the dose of fentanyl required to induce the patient to sit for spinal anesthesia and the pain intensity were evaluated. Moreover, the duration of analgesia and the total amount of morphine consumed in the first 24 h following surgery were evaluated, analyzed, and compared between the two study groups.

RESULTS

FICB and QLB demonstrated effective comparative postoperative analgesic profiles following acetabular fracture surgery; however, no significant differences in VAS values were observed between the two groups during the study. FICB experienced reduced cumulative fentanyl consumption during spinal anesthetic placement, whereas QLB had a significantly lower total morphine demand in the initial postoperative 24 h period.

CONCLUSION

The lateral QLB and FICB can be introduced as effective routes for analgesia in acetabular fracture surgery using the Stoppa method. . The study was prospectively registered in the clinical trials registry system, on 2021-02-17, with registration number: IRCT20191114045435N1.

摘要

背景

髋臼骨折手术后常伴有长时间、剧烈的围手术期疼痛,目前对于最佳止痛管理尚未达成共识。

目的

本研究旨在比较采用 Stoppa 入路行髋臼骨折手术的患者中,股外侧肌间隙阻滞(FICB)和竖脊肌平面阻滞(QLB)的镇痛效果。

方法

这是一项双盲、随机、非劣效性临床试验,纳入在伊朗德黑兰 Imam Hossein 医院接受椎管内麻醉的髋臼骨折手术的成年患者,将其随机分为两组:FICB 组(n=22)和 QLB 组(n=24)。所有参与者均使用视觉模拟评分(VAS)评估不同时间的疼痛强度。此外,还评估了诱导患者行椎管内麻醉时所需的芬太尼剂量以及疼痛强度。还评估和比较了两组研究中术后 24 小时内的镇痛持续时间和吗啡总消耗量。

结果

FICB 和 QLB 均能有效缓解髋臼骨折手术后的疼痛;然而,两组在研究期间的 VAS 值无显著差异。在椎管内麻醉置管期间,FICB 组芬太尼累积消耗量减少,而 QLB 组术后 24 小时内总吗啡需求量明显较低。

结论

在采用 Stoppa 入路的髋臼骨折手术中,外侧 QLB 和 FICB 均可作为有效的镇痛途径。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9608/10787012/b294b0c0063c/PRM2024-3720344.001.jpg

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