Department of Radiology and Nuclear Medicine, The First Hospital of HeBei Medical University, Shijiazhuang City, 050000, China.
Department of CTMRI, The Third Hospital of HeBei Medical University, Shijiazhuang, 050051, China.
Eur Spine J. 2024 Mar;33(3):1223-1229. doi: 10.1007/s00586-023-08110-8. Epub 2024 Jan 17.
PURPOSE: To investigate the clinical application value of the non-shared incentive diffusion imaging technique (ZOOM-DWI) diagnoses of cervical spondylotic myelopathy (CSM). METHODS: 49 CSM patients who presented from January 2022 to December 2022 were selected as the patient group, and 50 healthy volunteers are recruited as the control group. All subjects underwent conventional MRI and ZOOM-DWI of the cervical spine and neurologic mJOA scores in patients with CSM. The spinal ADC values of segments C2-3, C4-5, C5-6, and C6-7 are measured and analyzed in all subjects, with C5-6 being the most severe level of spinal canal compression in the patient group. In addition, the study also analyzes and compares the relationship between the C5-6 ADC value and mJOA score in the patient group. RESULTS: The mean ADC shows no significantly different levels in the control group. Among the ADC values at each measurement level in the patient group, except for C4-5 and C6-7 segments are not statistically significant, the remaining pair-wise comparisons all show statistically significant differences (F = 24.368, p < 0.001). And these individuals have the highest ADC value at C5-6. The C5-6 ADC value in the patient group is significantly higher compared with the ADC value in the control group (t = 9.414, p < 0.001), with statistical significance. The ADC value at the patient stenosis shows a significant negative correlation with the mJOA score (r = -0.493, p < 0.001). CONCLUSION: Cervical ZOOM-DWI can be applied to diagnose CSM, and spinal ADC value can use as reliable imaging data for diagnosing cervical myelopathy.
目的:探讨非共享激励扩散成像技术(ZOOM-DWI)诊断脊髓型颈椎病(CSM)的临床应用价值。
方法:选取 2022 年 1 月至 12 月收治的 49 例 CSM 患者为患者组,另选同期 50 名健康志愿者为对照组。所有受试者均行常规 MRI 及 ZOOM-DWI 颈椎扫描和患者的神经 mJOA 评分。测量并分析所有受试者 C2-3、C4-5、C5-6、C6-7 节段脊髓 ADC 值,患者组以椎管受压最严重的 C5-6 节段为研究对象。此外,还分析并比较了患者组 C5-6 ADC 值与 mJOA 评分的关系。
结果:对照组平均 ADC 值无明显差异。患者组各测量水平 ADC 值中,除 C4-5 及 C6-7 节段外,其余两两比较均差异有统计学意义(F = 24.368,p < 0.001),且均以 C5-6 节段 ADC 值最高。患者组 C5-6 节段 ADC 值明显高于对照组(t = 9.414,p < 0.001),差异有统计学意义。患者狭窄节段 ADC 值与 mJOA 评分呈显著负相关(r = -0.493,p < 0.001)。
结论:颈椎 ZOOM-DWI 可用于 CSM 的诊断,脊髓 ADC 值可作为诊断颈髓病的可靠影像学数据。
Eur J Radiol Open. 2018-12-12
Spine (Phila Pa 1976). 2014-7-1