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[年龄相关性白内障超声乳化术对原发性开角型青光眼眼压及虹膜角膜角参数的影响]

[The effect of phacoemulsification of age-related cataract on intraocular pressure and iridocorneal angle parameters in primary open-angle glaucoma].

作者信息

Antonov A A, Khderi Kh, Bersunkayev M K, Pateyuk L S

机构信息

Krasnov Research Institute of Eye Diseases, Moscow, Russia.

出版信息

Vestn Oftalmol. 2023;139(6):60-68. doi: 10.17116/oftalma202313906160.

Abstract

UNLABELLED

Cataract phacoemulsification with intraocular lens implantation significantly affects the morphology of the anterior chamber angle (ACA) and contributes to a reduction of intraocular pressure (IOP).

PURPOSE

This study investigates the changes in anterior chamber angle configuration and IOP level before and after cataract surgery in primary open-angle glaucoma (POAG) eyes, and assesses its possible relationship with the axial length of the eye.

MATERIAL AND METHODS

The study included 38 patients with immature senile cataract and compensated unoperated stage I-II POAG. Patients underwent anterior segment optical coherence tomography (AS-OCT) with measurement of the angle opening distance (AOD) and trabecular-iris space area (TISA) before and six weeks after the surgery, as well as axial length and corneal-compensated IOP (IOP).

RESULTS

After the surgery 92.11% of patients showed a decrease in IOP an average of 1.84±1.95 mm Hg (by 12.33±10.21% of the baseline); the maximum decrease in the IOP level was 8.35 mm Hg (by 40.97% of the baseline). AS-OCT data indicates that cataract phacoemulsification causes an increase in anterior chamber angle width: AOD increased from 0.510±0.175 to 0.771±0.156 mm, and TISA increased from 0.266±0.090 to 0.494±0.096 mm. The strongest correlations were found between the axial length, postoperative TISA increase (%TISA) and postoperative IOP reduction (% IOP). Postoperatively, specific changes could be observed in the trabecular meshwork in 28.95% of cases in the form of elongation and strain of the membrane.

CONCLUSIONS

Cataract extraction contributes to a significant reduction in IOP due to anterior chamber angle expansion, trabecular meshwork stretching, and improved aqueous outflow.

摘要

未标注

白内障超声乳化吸除联合人工晶状体植入术显著影响前房角(ACA)形态,并有助于降低眼压(IOP)。

目的

本研究调查原发性开角型青光眼(POAG)患者白内障手术前后前房角形态和眼压水平的变化,并评估其与眼轴长度的可能关系。

材料与方法

本研究纳入38例未成熟老年性白内障且处于未手术代偿期I-II级POAG患者。患者在手术前和手术后六周接受眼前节光学相干断层扫描(AS-OCT),测量房角开放距离(AOD)和小梁-虹膜空间面积(TISA),以及眼轴长度和角膜代偿眼压(IOP)。

结果

手术后,92.11%的患者眼压下降,平均下降1.84±1.95 mmHg(较基线下降12.33±10.21%);眼压水平最大下降8.35 mmHg(较基线下降40.97%)。AS-OCT数据表明,白内障超声乳化吸除术使前房角宽度增加:AOD从0.510±0.175增加到0.771±0.156 mm,TISA从0.266±0.090增加到0.494±0.096 mm。在眼轴长度、术后TISA增加(%TISA)和术后眼压降低(%IOP)之间发现了最强的相关性。术后,28.95%的病例小梁网出现特定变化,表现为膜的伸长和拉伸。

结论

白内障摘除术通过前房角扩张、小梁网拉伸和房水流出改善,有助于显著降低眼压。

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