Antonov A A, Khderi Kh, Bersunkayev M K, Pateyuk L S
Krasnov Research Institute of Eye Diseases, Moscow, Russia.
Vestn Oftalmol. 2023;139(6):60-68. doi: 10.17116/oftalma202313906160.
Cataract phacoemulsification with intraocular lens implantation significantly affects the morphology of the anterior chamber angle (ACA) and contributes to a reduction of intraocular pressure (IOP).
This study investigates the changes in anterior chamber angle configuration and IOP level before and after cataract surgery in primary open-angle glaucoma (POAG) eyes, and assesses its possible relationship with the axial length of the eye.
The study included 38 patients with immature senile cataract and compensated unoperated stage I-II POAG. Patients underwent anterior segment optical coherence tomography (AS-OCT) with measurement of the angle opening distance (AOD) and trabecular-iris space area (TISA) before and six weeks after the surgery, as well as axial length and corneal-compensated IOP (IOP).
After the surgery 92.11% of patients showed a decrease in IOP an average of 1.84±1.95 mm Hg (by 12.33±10.21% of the baseline); the maximum decrease in the IOP level was 8.35 mm Hg (by 40.97% of the baseline). AS-OCT data indicates that cataract phacoemulsification causes an increase in anterior chamber angle width: AOD increased from 0.510±0.175 to 0.771±0.156 mm, and TISA increased from 0.266±0.090 to 0.494±0.096 mm. The strongest correlations were found between the axial length, postoperative TISA increase (%TISA) and postoperative IOP reduction (% IOP). Postoperatively, specific changes could be observed in the trabecular meshwork in 28.95% of cases in the form of elongation and strain of the membrane.
Cataract extraction contributes to a significant reduction in IOP due to anterior chamber angle expansion, trabecular meshwork stretching, and improved aqueous outflow.
白内障超声乳化吸除联合人工晶状体植入术显著影响前房角(ACA)形态,并有助于降低眼压(IOP)。
本研究调查原发性开角型青光眼(POAG)患者白内障手术前后前房角形态和眼压水平的变化,并评估其与眼轴长度的可能关系。
本研究纳入38例未成熟老年性白内障且处于未手术代偿期I-II级POAG患者。患者在手术前和手术后六周接受眼前节光学相干断层扫描(AS-OCT),测量房角开放距离(AOD)和小梁-虹膜空间面积(TISA),以及眼轴长度和角膜代偿眼压(IOP)。
手术后,92.11%的患者眼压下降,平均下降1.84±1.95 mmHg(较基线下降12.33±10.21%);眼压水平最大下降8.35 mmHg(较基线下降40.97%)。AS-OCT数据表明,白内障超声乳化吸除术使前房角宽度增加:AOD从0.510±0.175增加到0.771±0.156 mm,TISA从0.266±0.090增加到0.494±0.096 mm。在眼轴长度、术后TISA增加(%TISA)和术后眼压降低(%IOP)之间发现了最强的相关性。术后,28.95%的病例小梁网出现特定变化,表现为膜的伸长和拉伸。
白内障摘除术通过前房角扩张、小梁网拉伸和房水流出改善,有助于显著降低眼压。