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全面描述 IBA myQA SRS 用于 SRS 和 SBRT 患者的特定质量保证。

Comprehensive characterisation of the IBA myQA SRS for SRS and SBRT patient specific quality assurance.

机构信息

Sydney West Radiation Oncology Network, Crown Princess Mary Cancer Centre, Westmead Hospital, Westmead, NSW, Australia.

Institute of Medical Physics, University of Sydney, Sydney, NSW, Australia.

出版信息

Phys Eng Sci Med. 2024 Mar;47(1):327-337. doi: 10.1007/s13246-023-01370-0. Epub 2024 Jan 18.

Abstract

The myQA SRS (IBA) is a new to market 2D complementary metal oxide semiconductor detector array with an active area 140 × 120 mm and 0.4 mm resolution, making it a potential real-time dosimetry alternative to radiochromic film for stereotactic plan verification. Characterisation of the device was completed to assess performance. The dosimetric properties of the device were assessed for 6FF and 6FFF beams from a Varian TrueBeam STx with high definition multileaf collimator. Clinical suitability of the device for Patient Specific Quality Assurance was verified using ten SRS/SBRT plans, compared against other detectors, as well as multi leaf collimator (MLC) tests including picket fence and chair. Gamma analysis was performed using myQA software with criteria of 4%/1 mm. The device demonstrated compliance with recommended specifications for basic tests. After the required warm-up period, the maximum deviation in detector signal from initial readings was 0.2%. Short-term and long-term reproducibility was 0.1% (6FF) and 1.0% (6FFF), respectively. Dose linearity was within 0.3% (6FF) and 0.7% (6FFF) and dose-rate dependence within 1.7% (6FF) and 2.9% (6FFF) and were verified with a Farmer type ionization chamber (PTW 30013). Angular dependence was quantified for coplanar and non-coplanar situations. Output factors and beam profiles measured on the device showed agreement within 1% of baseline RAZOR diode (IBA) and CC04 ionisation chamber (IBA) measurements for field sizes 1 × 1 to 10 × 10 cm. The minimum gamma (4%/1 mm) pass rates for MLC-pattern tests were 96.5% and 98.1% for the myQA SRS and film, respectively. The average gamma (4%/1 mm) pass rates for SBRT and SRS plans were 98.8% and 99.8% respectively. This work represents one of the first studies performed on the commissioning and performance characterisation of this novel device, demonstrating its accuracy and reliability, making it highly useful as a film alternative in stereotactic treatment plan verification.

摘要

IBA 的 myQA SRS 是一款全新的市场上的 2D 互补金属氧化物半导体探测器阵列,其有效面积为 140×120mm,分辨率为 0.4mm,这使其成为立体定向计划验证中替代放射色胶片的实时剂量测定的潜在选择。为了评估性能,对该设备进行了特性描述。使用具有高清晰度多叶准直器的瓦里安 TrueBeam STx 的 6FF 和 6FFF 光束对设备的剂量学特性进行了评估。通过与其他探测器以及多叶准直器(MLC)测试(包括尖桩围栏和椅子)相比,使用十个 SRS/SBRT 计划验证了该设备用于患者特定质量保证的临床适用性。使用 myQA 软件进行伽马分析,标准为 4%/1mm。该设备符合基本测试的推荐规格。在经过所需的预热期后,探测器信号与初始读数的最大偏差为 0.2%。短期和长期重复性分别为 0.1%(6FF)和 1.0%(6FFF)。剂量线性度在 0.3%(6FF)和 0.7%(6FFF)以内,剂量率依赖性在 1.7%(6FF)和 2.9%(6FFF)以内,并使用 Farmer 型电离室(PTW 30013)进行了验证。对共面和非共面情况进行了角度依赖性量化。在设备上测量的输出因子和射束轮廓与基线 RAZOR 二极管(IBA)和 CC04 电离室(IBA)的测量值相比,在 1×1 至 10×10cm 的射野尺寸下,一致性在 1%以内。对于 MLC 模式测试,myQA SRS 和胶片的最小伽马(4%/1mm)通过率分别为 96.5%和 98.1%。SBRT 和 SRS 计划的平均伽马(4%/1mm)通过率分别为 98.8%和 99.8%。这项工作代表了对这种新型设备的调试和性能特性进行的首批研究之一,证明了它的准确性和可靠性,使其成为立体定向治疗计划验证中替代胶片的非常有用的工具。

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