Suppr超能文献

横断面研究调查双侧下肢凹陷性水肿的凹陷恢复时间与血清白蛋白水平之间的关系。

Cross-sectional study investigating the relationship between pit recovery time and serum albumin levels in bilateral lower extremity pitting oedema.

机构信息

Department of Community Medicine, Kameyama, Mie University School of Medicine, Tsu, Mie, Japan

Department of Internal Medicine, Kameyama Municipal Medical Center, Kameyama, Mie, Japan.

出版信息

BMJ Open. 2024 Jan 18;14(1):e079327. doi: 10.1136/bmjopen-2023-079327.

Abstract

OBJECTIVES

In this study, we re-evaluated the relationship between pit recovery time (PRT) and serum albumin levels and elucidated the factors influencing PRT.

DESIGN

Cross-sectional study.

SETTING

Patients who visited the outpatient department or were admitted to a small urban hospital in Japan.

PARTICIPANTS

135 adult Japanese patients with bilateral lower extremity pitting oedema.

INTERVENTIONS

: this study assessed the correlation between PRT and serum albumin levels, calculated the predictive accuracy for identifying a group with low albumin levels when the PRT of the lower leg was <40 s, and identified variables that influence PRT.

RESULTS

We found no significant correlation between lower leg PRT and serum albumin levels. Furthermore, a PRT of <40 s was largely ineffective in predicting low albumin levels. Factors influencing PRT included the diagnosis of malnutrition oedema, examinations conducted during hospitalisation, diagnosis of cardiac oedema, use of diuretics, thickness of the lower limb soft tissue, serum creatinine level, estimated right ventricular systolic pressure (RVSP), age, serum albumin level, potassium level and blood urea nitrogen to serum creatinine ratio. Notable correlations with PRT were observed in relation to lower limb soft tissue thickness, age and estimated RVSP.

CONCLUSIONS

Given that the PRT is influenced by multiple factors, its correlation with serum albumin levels is weak. Thus, predicting hypoalbuminaemia based solely on PRT is inaccurate.

摘要

目的

本研究重新评估了凹陷性水肿平复时间(PRT)与血清白蛋白水平之间的关系,并阐明了影响 PRT 的因素。

设计

横断面研究。

地点

在日本一家小型城市医院就诊的门诊或住院患者。

参与者

135 例双侧下肢凹陷性水肿的成年日本患者。

干预措施

评估 PRT 与血清白蛋白水平之间的相关性,计算当小腿 PRT<40s 时识别低白蛋白血症组的预测准确性,并确定影响 PRT 的变量。

结果

我们未发现小腿 PRT 与血清白蛋白水平之间存在显著相关性。此外,PRT<40s 对低白蛋白血症的预测效果不佳。影响 PRT 的因素包括营养不良性水肿的诊断、住院期间的检查、心脏水肿的诊断、利尿剂的使用、下肢软组织的厚度、血清肌酐水平、估计右心室收缩压(RVSP)、年龄、血清白蛋白水平、钾水平和血尿素氮与血清肌酐的比值。与 PRT 有显著相关性的因素包括下肢软组织厚度、年龄和估计的 RVSP。

结论

由于 PRT 受多种因素影响,其与血清白蛋白水平的相关性较弱。因此,仅根据 PRT 预测低白蛋白血症是不准确的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a40/10806623/463d8912268a/bmjopen-2023-079327f01.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验