Suppr
超能文献

职业性粉尘暴露作为导致肺功能损害的危险因素。

Occupational Dust Exposure as a Risk Factor for Developing Lung Function Impairment.

机构信息

From the School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden (J.S.); Department of Occupational and Environmental Medicine, Örebro University Hospital, Örebro, Sweden (I.-L.B.); Department of Respiratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden (J.S.); Department of Medical Sciences, Respiratory, Allergy & Sleep Research, Uppsala University, Uppsala, Sweden (C.J.); and Department of Occupational and Environmental Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden (L.A.).

出版信息

J Occup Environ Med. 2024 Mar 1;66(3):e93-e98. doi: 10.1097/JOM.0000000000003036. Epub 2024 Jan 19.

DOI:10.1097/JOM.0000000000003036

PMID:38242136

Abstract

OBJECTIVE

Dust exposure is high in several industries. We investigated associations of exposure in paper mills, wood pellet plants, and iron foundries with lung function impairment.

METHODS

Respirable silica, inhalable paper dust, or inhalable wood dust were collected as personal samples and spirometry was performed. Multiple linear regression analyzed associations with FEV 1 %pred and FVC%pred.

RESULTS

Wood pellet workers with high exposure to inhalable dust had lower FEV 1 %pred (95% CI) (-9.4 [-16 to -2.6]) and FVC%pred (-9.8 [-15 to -4.0]) compared with lowest exposure level. Workers at paper mills and foundries had no dose-dependent association but lower FEV 1 %pred and FVC%pred than in workers at wood pellets plants.

CONCLUSIONS

Increased exposure to inhalable wood dust is associated with decreased lung function. Foundry and paper mill workers have generally lower lung function than wood pellet workers. Spirometry should be considered in workers in industries with airborne particulate matter pollution.

摘要

目的

在一些行业中，粉尘暴露水平较高。我们研究了纸浆厂、木屑颗粒厂和铸造厂的粉尘暴露与肺功能损害之间的关系。

方法

采集可呼吸性二氧化硅、可吸入性纸尘或可吸入性木尘作为个人样本，并进行肺活量测定。多线性回归分析与 FEV 1 %pred 和 FVC%pred 的相关性。

结果

与最低暴露水平相比，高暴露于可吸入性粉尘的木屑颗粒厂工人的 FEV 1 %pred（95%CI）（-9.4[-16 至-2.6]）和 FVC%pred（-9.8[-15 至-4.0]）更低。纸浆厂和铸造厂的工人没有剂量依赖性关联，但 FEV 1 %pred 和 FVC%pred 均低于木屑颗粒厂的工人。