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乳房手术后的慢性疼痛:发生率、风险因素及对生活质量的影响。

Chronic pain after breast surgery: incidence, risk factors and impact on quality of life.

机构信息

Department of Anaesthesiology, Centro Hospitalar Universitário São João, Alameda Prof. Hernâni Monteiro, Porto, Portugal.

Department of Anaesthesiology, Centro Hospitalar Universitário São João, Alameda Prof. Hernâni Monteiro, Porto, Portugal.

出版信息

Rev Esp Anestesiol Reanim (Engl Ed). 2024 Apr;71(4):274-281. doi: 10.1016/j.redare.2024.01.002. Epub 2024 Jan 18.

Abstract

INTRODUCTION AND OBJECTIVES

Breast cancer is the most frequently diagnosed malignancy, and chronic pain after breast surgery (CPBS) is an increasingly recognized therapy-related problem. We evaluated CPBS incidence, characteristics, associated factors, and impact on patient quality of life (QoL).

MATERIALS AND METHODS

Six-month observational prospective study conducted in patients undergoing breast surgery in a tertiary university hospital. Data were collected using several questionnaires: Pain Catastrophizing Scale, Brief Pain Inventory-Short Form, Douleur Neuropathique 4 Questionnaire, and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire and its Breast Cancer Module.

RESULTS

A total of 112 patients completed the study. Approximately, one third (34.8%) developed CPBS, and almost all with potentially neuropathic pain. CPBS interfered with patients' daily life and reduced their QoL. Diabetes (p = 0.028), catastrophizing (p = 0.042), and acute postoperative pain severity (p < 0.001) were associated with CPBS.

CONCLUSIONS

This study broadens our understanding of CPBS and shows the impact of this syndrome. Healthcare workers need to be aware of CPBS and take steps to prevent and treat it, and provide patients with adequate information.

摘要

简介和目的

乳腺癌是最常见的恶性肿瘤,乳腺癌手术后慢性疼痛(CPBS)是一种日益被认识到的与治疗相关的问题。我们评估了 CPBS 的发生率、特征、相关因素以及对患者生活质量(QoL)的影响。

材料和方法

这是一项在一家三级大学医院接受乳房手术的患者中进行的为期 6 个月的前瞻性观察研究。使用了几个问卷来收集数据:疼痛灾难化量表、简明疼痛量表-短表、神经性疼痛 4 项问卷、欧洲癌症研究与治疗组织生活质量问卷及其乳腺癌模块。

结果

共有 112 名患者完成了研究。大约三分之一(34.8%)的患者出现 CPBS,几乎所有患者都有潜在的神经性疼痛。CPBS 干扰了患者的日常生活,降低了他们的生活质量。糖尿病(p=0.028)、灾难化(p=0.042)和急性术后疼痛严重程度(p<0.001)与 CPBS 相关。

结论

这项研究拓宽了我们对 CPBS 的理解,并展示了该综合征的影响。医疗保健工作者需要意识到 CPBS 的存在,并采取措施预防和治疗它,为患者提供足够的信息。

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