Costa Natalia Silva, Oliveira Laura Maria Andrade, Rio-Tinto Andre, Pinto Isabella Bittencourt Ferreira, Oliveira Ana Elisa Almeida Santos, Santana Julia de Deus, Santos Laiane Ferreira, Costa Rayssa Santos Nogueira, Marinho Penelope Saldanha, Fracalanzza Sergio Eduardo Longo, Teixeira Lucia Martins, Pinto Tatiana Castro Abreu
Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, Brazil.
Faculdade de Medicina, Maternidade Escola, Universidade Federal do Rio de Janeiro, Rio de Janeiro 22240-000, Brazil.
Antibiotics (Basel). 2024 Jan 16;13(1):85. doi: 10.3390/antibiotics13010085.
(Group B ; GBS) is a leading cause of neonatal invasive disease worldwide. GBS can colonize the human gastrointestinal and genitourinary tracts, and the anovaginal colonization of pregnant women is the main source for neonatal infection. , in turn, can colonize the human upper respiratory, gastrointestinal, and genitourinary tracts but has rarely been observed causing disease. However, in the last years, has been increasingly associated with human infections, mainly in the bloodstream and gastrointestinal and genitourinary tracts. Although anovaginal screening for GBS is common during pregnancy, data regarding the anovaginal colonization of pregnant women by are still scarce. Here, we show that during the assessment of anovaginal GBS colonization rates among pregnant women living in Rio de Janeiro, Brazil, was also commonly detected, and isolates presented a similar colony morphology and color pattern to GBS in chromogenic media. GBS was detected in 48 (12%) while was detected in 17 (4.3%) of the 399 anovaginal samples analyzed. The use of antibiotics during pregnancy and history of urinary tract infections and sexually transmitted infections were associated with the presence of . In turn, previous preterm birth was associated with the presence of GBS ( < 0.05). The correlation of GBS and with relevant clinical features of pregnant women in Rio de Janeiro, Brazil, highlights the need for the further investigation of these important bacteria in relation to this special population.
B组(无乳链球菌;GBS)是全球新生儿侵袭性疾病的主要病因。无乳链球菌可定植于人类胃肠道和泌尿生殖道,孕妇的肛门阴道定植是新生儿感染的主要来源。[未提及的某种细菌]反过来可定植于人类上呼吸道、胃肠道和泌尿生殖道,但很少观察到其致病情况。然而,在过去几年中,[未提及的某种细菌]与人类感染的关联日益增加,主要发生在血液、胃肠道和泌尿生殖道。尽管孕期对无乳链球菌进行肛门阴道筛查很常见,但关于孕妇肛门阴道被[未提及的某种细菌]定植的数据仍然很少。在此,我们表明,在评估巴西里约热内卢孕妇的肛门阴道无乳链球菌定植率时,也经常检测到[未提及的某种细菌],并且在显色培养基中,[未提及的某种细菌]分离株呈现出与无乳链球菌相似的菌落形态和颜色模式。在分析的399份肛门阴道样本中,48份(12%)检测到无乳链球菌,17份(4.3%)检测到[未提及的某种细菌]。孕期使用抗生素以及有尿路感染和性传播感染病史与[未提及的某种细菌]的存在相关。反过来,既往早产与无乳链球菌的存在相关(P<0.05)。巴西里约热内卢无乳链球菌和[未提及的某种细菌]与孕妇相关临床特征的相关性,凸显了针对这一特殊人群进一步研究这些重要细菌的必要性。