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显微切割睾丸取精术

Microdissection Testicular Sperm Extraction.

作者信息

Brant Aaron, Schlegel Peter N

机构信息

Department of Urology, New York-Presbyterian Hospital, Weill Cornell Medicine, New York, New York.

出版信息

Semin Reprod Med. 2023 Nov;41(6):267-272. doi: 10.1055/s-0043-1777833. Epub 2024 Jan 23.

Abstract

Nonobstructive azoospermia (NOA) is among the most common causes of male infertility. For men with NOA seeking fertility treatment, microdissection testicular sperm extraction (microTESE) is the best option for retrieving sperm, which can be used with in vitro fertilization-intracytoplasmic sperm injection to achieve pregnancy in their partner. With the aid of the operating microscope, microTESE allows for thorough evaluation of the testis tissue and selection of seminiferous tubules that appear most capable of sperm production. Rates of success with microTESE vary depending on the underlying cause of NOA and the center at which the procedure is performed. Not all patients are candidates for microTESE, and those who are candidates should be counseled on the likelihood of sperm retrieval and the potential for changes in postoperative testis function.

摘要

非梗阻性无精子症(NOA)是男性不育的最常见原因之一。对于寻求生育治疗的NOA男性患者,显微外科睾丸精子提取术(microTESE)是获取精子的最佳选择,所获精子可用于体外受精-卵胞浆内单精子注射,以使配偶受孕。借助手术显微镜,microTESE能够对睾丸组织进行全面评估,并选择最有可能产生精子的生精小管。microTESE的成功率因NOA的潜在病因以及实施该手术的中心而异。并非所有患者都适合进行microTESE,对于适合的患者,应就获取精子的可能性以及术后睾丸功能变化的可能性给予咨询。

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