Abrams R, Taylor M A, Volavka J
Am J Psychiatry. 1987 Mar;144(3):327-9. doi: 10.1176/ajp.144.3.327.
Six right-unilateral and bilateral ECTs were equally effective in reducing Hamilton Rating Scale for Depression scores in 34 melancholic patients whose EEG symmetry did not change after ECT. However, a substantial therapeutic advantage was recorded for bilateral ECT in those patients whose EEG symmetry changed. Accentuation of ECT-induced EEG slowing over the right hemisphere was associated with right-unilateral ECT and a lesser treatment response, suggesting that the therapeutic advantage reported by some investigators for bilateral over right-unilateral ECT may be attributed to a poor outcome experienced by those unilateral ECT patients who developed right-sided EEG slowing.
对于34例忧郁症患者，6次右侧单侧和双侧电休克治疗在降低汉密尔顿抑郁量表评分方面效果相同，这些患者的脑电图对称性在电休克治疗后未发生变化。然而，对于脑电图对称性发生变化的患者，双侧电休克治疗显示出显著的治疗优势。右侧单侧电休克治疗与右侧半球脑电图减慢加重以及治疗反应较差相关，这表明一些研究者报道的双侧电休克治疗优于右侧单侧电休克治疗的治疗优势，可能归因于那些出现右侧脑电图减慢的单侧电休克治疗患者预后较差。
