鼻腔神经胶质异位症 1 例，易误诊为席纹状硬化性纤维瘤/胶原瘤。
A Case of Nasal Glial Heterotopia That Can Be Misdiagnosed as Storiform Patterned Sclerotic Fibroma/Collagenoma.
机构信息
Department of Pathology, Hacettepe University, Faculty of Medicine, ANKARA, TURKEY.
Department of Plastic Reconstructive and Aesthetic Surgery, Hacettepe University, Faculty of Medicine, ANKARA, TURKEY.
出版信息
Turk Patoloji Derg. 2024;40(2):134-137. doi: 10.5146/tjpath.2023.13053.
OBJECTIVE
Nasal glioma, also known as nasal glial heterotopia, is a rare tumor-like lesion that often affects newborns or infants with no hereditary predisposition.
CASE REPORT
A 4-year-old child with a growth on the nasal dorsum since birth was diagnosed with nasal glial heterotopia/nasal glioma. The lesion showed a sclerotic fibroma/collagenoma-like storiform pattern with entrapped glial tissue that was S100 and GFAP positive.
CONCLUSION
When a biopsy of the nasal dorsum demonstrates sclerotic microscopic findings with a storiform pattern, nasal glioma should be considered before making a diagnosis in the collagen-rich tissue spectrum (collagenoma or Gardner's fibroma), and an immunohistochemical panel should be requested to demonstrate the presence of an unrecognized light microscopically visible glial component.
目的
鼻神经胶质瘤，又称鼻神经胶质异位，是一种罕见的肿瘤样病变，常发生于无遗传倾向的新生儿或婴儿。
病例报告
一名 4 岁儿童自出生起鼻背部就有一个肿物，被诊断为鼻神经胶质异位/鼻神经胶质瘤。病变表现为硬化性纤维瘤/胶原瘤样席纹状模式，伴有被囚绕的神经胶质组织，S100 和 GFAP 阳性。
结论
当鼻背部活检显示出硬化性微观表现和席纹状模式时，在做出富含胶原组织谱（胶原瘤或 Gardner 纤维瘤）的诊断之前，应考虑鼻神经胶质瘤的可能性，并应请求免疫组织化学小组来证明存在未被识别的光镜下可见的神经胶质成分。
Zotero 插件