[新生儿红斑狼疮各系统表现及预后的研究进展]
[Research progress on the manifestations and prognosis of neonatal lupus erythematosus in various systems].
作者信息
Shao Shu-Ming, Zhang Yi-Min, Zhang Xiao-Rui
机构信息
Department of Pediatrics, Peking University People's Hospital, Beijing 100044, China (Zhang X-R, Email: icy.zhang@ 163. com).
出版信息
Zhongguo Dang Dai Er Ke Za Zhi. 2024 Jan 15;26(1):81-85. doi: 10.7499/j.issn.1008-8830.2306125.
Neonatal lupus erythematosus (NLE) is caused by the transmission of maternal anti-Ro/SSA antibodies, anti-La/SSB antibodies, and other autoantibodies to the fetus through the placenta. Usually, with the disappearance of autoantibodies in the children's body, abnormal changes in the mucocutaneous, blood system, and digestive system can spontaneously subside, but the damage to various systems caused by autoantibodies may persist for a long time. This article provides a comprehensive review of the manifestations and prognosis of NLE in various systems, including mucocutaneous, blood system, circulatory system, nervous system, digestive system, respiratory system, aiming to provide reference for clinical work.
新生儿红斑狼疮（NLE）是由母体的抗Ro/SSA抗体、抗La/SSB抗体及其他自身抗体经胎盘传递给胎儿所致。通常，随着患儿体内自身抗体的消失，皮肤黏膜、血液系统及消化系统的异常改变可自行消退，但自身抗体对各系统造成的损害可能长期持续。本文全面综述了NLE在皮肤黏膜、血液系统、循环系统、神经系统、消化系统、呼吸系统等各系统的表现及预后，旨在为临床工作提供参考。
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