Tribouilloy C, Hermida J S, Jarry G, Rey J L, Quiret J C, Bernasconi P
Ann Cardiol Angeiol (Paris). 1987 Jan;36(1):7-12.
The objective of this study is to investigate the significance of the occurrence of an upward shift of the ST segment curing a stress test in patients with no previous history of myocardial infarction. Over 10 years, totalling 9,500 stress tests, we have collected 10 cases. They always concern men including one with angina on exertion, one with spontaneous angina, one with spontaneous angina occurring at the end of an intense stress, and 7 with mixed angina. None of them had a previous history of myocardial infarction or documented spastic angina. The upward shift of the ST segment occurred 9 times during stress and once during recovery. 9 patients had a coronary arteriogram with in 8 cases severe fixed coronary lesions. The patient with the upward shift of ST during the recovery period had a normal coronary arteriogram with a positive methylergometrin test. There is a good correlation between the appearance of an upward shift of ST during stress in the anterior derivations and a significant involvement of the anterior interventricular artery. In our series, there were no complications, especially myocardial infarction, in the immediate period following the stress test. 7 patients underwent an aorto-coronary by-pass. The 10 patients are presently asymptomatic after a 47 months follow-up. The occurrence of an upward shift of ST during stress, in the absence of a previous history of myocardial infarction, represents in more than 80 p. cent of the cases the existence of severe coronary lesions leading to hospitalization and the immediate performance of a coronary arteriogram.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究的目的是调查在无心肌梗死既往史的患者中,进行负荷试验时ST段上移的发生意义。在10年期间,共进行了9500次负荷试验,我们收集到10例病例。这些病例均为男性,其中1例为劳力性心绞痛,1例为自发性心绞痛,1例为剧烈负荷末期出现的自发性心绞痛,7例为混合性心绞痛。他们均无心肌梗死既往史或有记录的痉挛性心绞痛病史。ST段上移在负荷期间出现9次,在恢复期间出现1次。9例患者进行了冠状动脉造影,其中8例有严重的固定性冠状动脉病变。在恢复期出现ST段上移的患者冠状动脉造影正常,但麦角新碱试验阳性。前壁导联在负荷时ST段上移的出现与前降支动脉的显著受累之间存在良好的相关性。在我们的系列研究中,负荷试验后即刻无并发症,尤其是无心肌梗死发生。7例患者接受了主动脉-冠状动脉搭桥术。经过47个月的随访,这10例患者目前均无症状。在无心肌梗死既往史的情况下,负荷时ST段上移的发生在超过80%的病例中代表存在严重冠状动脉病变,需要住院并立即进行冠状动脉造影。(摘要截选至250词)