Yang Zihao, Yan Lin, Zhang Wenliang, Qi Jia, An Wenjing, Yao Kai
Institute of Visual Neuroscience and Stem Cell Engineering, Wuhan University of Science and Technology, Wuhan, China.
College of Life Sciences and Health, Wuhan University of Science and Technology, Wuhan, China.
Front Neurosci. 2024 Jan 17;18:1265630. doi: 10.3389/fnins.2024.1265630. eCollection 2024.
Color blindness is a retinal disease that mainly manifests as a color vision disorder, characterized by achromatopsia, red-green color blindness, and blue-yellow color blindness. With the development of technology and progress in theory, extensive research has been conducted on the genetic basis of color blindness, and various approaches have been explored for its treatment. This article aims to provide a comprehensive review of recent advances in understanding the pathological mechanism, clinical symptoms, and treatment options for color blindness. Additionally, we discuss the various treatment approaches that have been developed to address color blindness, including gene therapy, pharmacological interventions, and visual aids. Furthermore, we highlight the promising results from clinical trials of these treatments, as well as the ongoing challenges that must be addressed to achieve effective and long-lasting therapeutic outcomes. Overall, this review provides valuable insights into the current state of research on color blindness, with the intention of informing further investigation and development of effective treatments for this disease.
色盲是一种视网膜疾病,主要表现为色觉障碍,其特征为全色盲、红绿色盲和蓝黄色盲。随着技术的发展和理论的进步,人们对色盲的遗传基础进行了广泛研究,并探索了多种治疗方法。本文旨在全面综述色盲病理机制、临床症状及治疗选择方面的最新进展。此外,我们还讨论了为治疗色盲而开发的各种治疗方法,包括基因治疗、药物干预和视觉辅助器具。此外,我们强调了这些治疗方法临床试验取得的有前景的结果,以及为实现有效和持久治疗效果必须应对的持续挑战。总体而言,本综述为色盲研究的现状提供了有价值的见解,旨在为该疾病的进一步研究和有效治疗方法的开发提供参考。