University of Michigan Medical School, Ann Arbor, Michigan.
University of Michigan Medical School, Ann Arbor, Michigan.
J Surg Res. 2024 Apr;296:418-424. doi: 10.1016/j.jss.2023.12.051. Epub 2024 Feb 5.
INTRODUCTION: For women ≥70 y old with early-stage hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer, the national guidelines recommend the omission of sentinel lymph node biopsy (SLNB) and post-lumpectomy radiotherapy. However, national-level data suggest these treatments remain common. We utilized a survey-based approach to explore patient-level factors driving overutilization. METHODS: We recruited women ≥70 y old with early-stage hormone receptor-positive/human epidermal growth factor receptor 2-negative breast cancer within 6 mo of surgery. An exploratory cross-sectional survey captured information on offered and pursued treatments, the importance of patient-centered outcomes, and the influence of each outcome on treatment decision-making. Descriptive statistics were used for analysis. RESULTS: 31/51 patients completed the survey with a response rate of 61%. Most patients (86%) received a lumpectomy. Twenty-eight percent of patients received SLNB, and 56% of lumpectomy patients underwent adjuvant radiotherapy. When considering treatment options, the patient-centered outcomes, most important for decision-making, were overall survival, breast-specific survival, and preventing local recurrence, while breast appearance, financial costs, and avoiding the need for pills (endocrine therapy) were the least important. CONCLUSIONS: Patients' treatment decisions align with their values. The correlation between patient-stated values and treatment decisions suggests a perceived mortality benefit of low-value SLNB and radiotherapy. These findings can inform targeted efforts to deimplement low-value care in breast cancer through patient-focused tools and education.
简介:对于 70 岁及以上、早期激素受体阳性、人表皮生长因子受体 2 阴性的乳腺癌女性,国家指南建议省略前哨淋巴结活检(SLNB)和保乳术后放疗。然而,国家级数据表明这些治疗方法仍然很常见。我们采用基于调查的方法来探讨导致过度治疗的患者层面因素。 方法:我们招募了 70 岁及以上、早期激素受体阳性/人表皮生长因子受体 2 阴性乳腺癌、术后 6 个月内的女性。一项探索性横断面调查记录了提供和追求的治疗方法、以患者为中心的治疗结果的重要性以及每个结果对治疗决策的影响。采用描述性统计方法进行分析。 结果:31/51 名患者完成了调查,应答率为 61%。大多数患者(86%)接受了保乳术。28%的患者接受了 SLNB,56%的保乳术患者接受了辅助放疗。在考虑治疗方案时,对决策最重要的患者为中心的治疗结果是总生存率、乳腺癌特异性生存率和预防局部复发,而乳房外观、经济成本和避免服用药物(内分泌治疗)则是最不重要的。 结论:患者的治疗决策与其价值观一致。患者陈述的价值观与治疗决策之间的相关性表明,低价值 SLNB 和放疗具有可感知的生存获益。这些发现可以通过以患者为中心的工具和教育为基础,为有针对性地减少乳腺癌中低价值治疗提供信息。
Zhonghua Zhong Liu Za Zhi. 2016-7
BMC Health Serv Res. 2024-12-28