文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

了解老年乳腺癌女性的治疗决策:一项基于调查的研究。

Understanding Treatment Decision-Making in Older Women With Breast Cancer: A Survey-Based Study.

机构信息

University of Michigan Medical School, Ann Arbor, Michigan.

University of Michigan Medical School, Ann Arbor, Michigan.

出版信息

J Surg Res. 2024 Apr;296:418-424. doi: 10.1016/j.jss.2023.12.051. Epub 2024 Feb 5.


DOI:10.1016/j.jss.2023.12.051
PMID:38320360
Abstract

INTRODUCTION: For women ≥70 y old with early-stage hormone receptor-positive, human epidermal growth factor receptor 2-negative breast cancer, the national guidelines recommend the omission of sentinel lymph node biopsy (SLNB) and post-lumpectomy radiotherapy. However, national-level data suggest these treatments remain common. We utilized a survey-based approach to explore patient-level factors driving overutilization. METHODS: We recruited women ≥70 y old with early-stage hormone receptor-positive/human epidermal growth factor receptor 2-negative breast cancer within 6 mo of surgery. An exploratory cross-sectional survey captured information on offered and pursued treatments, the importance of patient-centered outcomes, and the influence of each outcome on treatment decision-making. Descriptive statistics were used for analysis. RESULTS: 31/51 patients completed the survey with a response rate of 61%. Most patients (86%) received a lumpectomy. Twenty-eight percent of patients received SLNB, and 56% of lumpectomy patients underwent adjuvant radiotherapy. When considering treatment options, the patient-centered outcomes, most important for decision-making, were overall survival, breast-specific survival, and preventing local recurrence, while breast appearance, financial costs, and avoiding the need for pills (endocrine therapy) were the least important. CONCLUSIONS: Patients' treatment decisions align with their values. The correlation between patient-stated values and treatment decisions suggests a perceived mortality benefit of low-value SLNB and radiotherapy. These findings can inform targeted efforts to deimplement low-value care in breast cancer through patient-focused tools and education.

摘要

简介:对于 70 岁及以上、早期激素受体阳性、人表皮生长因子受体 2 阴性的乳腺癌女性,国家指南建议省略前哨淋巴结活检(SLNB)和保乳术后放疗。然而,国家级数据表明这些治疗方法仍然很常见。我们采用基于调查的方法来探讨导致过度治疗的患者层面因素。 方法:我们招募了 70 岁及以上、早期激素受体阳性/人表皮生长因子受体 2 阴性乳腺癌、术后 6 个月内的女性。一项探索性横断面调查记录了提供和追求的治疗方法、以患者为中心的治疗结果的重要性以及每个结果对治疗决策的影响。采用描述性统计方法进行分析。 结果:31/51 名患者完成了调查,应答率为 61%。大多数患者(86%)接受了保乳术。28%的患者接受了 SLNB,56%的保乳术患者接受了辅助放疗。在考虑治疗方案时,对决策最重要的患者为中心的治疗结果是总生存率、乳腺癌特异性生存率和预防局部复发,而乳房外观、经济成本和避免服用药物(内分泌治疗)则是最不重要的。 结论:患者的治疗决策与其价值观一致。患者陈述的价值观与治疗决策之间的相关性表明,低价值 SLNB 和放疗具有可感知的生存获益。这些发现可以通过以患者为中心的工具和教育为基础,为有针对性地减少乳腺癌中低价值治疗提供信息。

相似文献

[1]
Understanding Treatment Decision-Making in Older Women With Breast Cancer: A Survey-Based Study.

J Surg Res. 2024-4

[2]
Trends in Breast Cancer Treatment De-Implementation in Older Patients with Hormone Receptor-Positive Breast Cancer: A Mixed Methods Study.

Ann Surg Oncol. 2021-2

[3]
Outcomes After Sentinel Lymph Node Biopsy and Radiotherapy in Older Women With Early-Stage, Estrogen Receptor-Positive Breast Cancer.

JAMA Netw Open. 2021-4-1

[4]
Patient Perspectives on Treatment Options for Older Women With Hormone Receptor-Positive Breast Cancer: A Qualitative Study.

JAMA Netw Open. 2020-9-1

[5]
Using Tailored Messages to Target Overuse of Low-Value Breast Cancer Care in Older Women.

J Surg Res. 2022-2

[6]
Avoiding Overtreatment of Women ≥70 With Early-Stage Breast Cancer: A Provider-Level Deimplementation Strategy.

J Surg Res. 2023-4

[7]
Assessment of Oncologists' Perspectives on Omission of Sentinel Lymph Node Biopsy in Women 70 Years and Older With Early-Stage Hormone Receptor-Positive Breast Cancer.

JAMA Netw Open. 2022-8-1

[8]
[Feasibility analysis of sentinel lymph node biopsy in patients with breast cancer after local lumpectomy].

Zhonghua Zhong Liu Za Zhi. 2016-7

[9]
Eight-year follow up result of the OTOASOR trial: The Optimal Treatment Of the Axilla - Surgery Or Radiotherapy after positive sentinel lymph node biopsy in early-stage breast cancer: A randomized, single centre, phase III, non-inferiority trial.

Eur J Surg Oncol. 2017-4

[10]
Breast cancer hormone receptor negativity, triple-negative type, mastectomy and not receiving adjuvant radiotherapy were associated with axillary recurrence after sentinel lymph node biopsy.

Asian J Surg. 2019-5-30

引用本文的文献

[1]
Factors associated with patients' demand for low-value care: a scoping review.

BMC Health Serv Res. 2024-12-28

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索