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减瘤手术及腹腔热灌注化疗在结直肠癌腹膜转移治疗中的作用

Role of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy in the Management of Colorectal Peritoneal Metastases.

作者信息

Shah Rupen, Gangi Alexandra

机构信息

Division of Surgical Oncology, Henry Ford Cancer Institute/Henry Ford Health, Detroit, Michigan.

Division of Surgical Oncology, Cedars Sinai Medical Center, Los Angeles, California.

出版信息

Clin Colon Rectal Surg. 2023 Mar 13;37(2):90-95. doi: 10.1055/s-0042-1758759. eCollection 2024 Mar.

Abstract

Peritoneal metastases from colon cancer are a particularly challenging disease process given the limited response to systemic chemotherapy. In patients with isolated peritoneal metastases, cytoreductive surgery with hyperthermic intraperitoneal chemotherapy offers a potential treatment option to these patients with limited peritoneal metastases as long as a complete cytoreduction is achieved. Decision about a patient's candidacy for this treatment modality should be undertaken by a multidisciplinary group at expert centers.

摘要

鉴于结肠癌腹膜转移对全身化疗的反应有限,它是一个特别具有挑战性的疾病过程。对于孤立性腹膜转移患者,只要能实现完全细胞减灭,细胞减灭术联合腹腔内热化疗为这些腹膜转移有限的患者提供了一种潜在的治疗选择。关于患者是否适合这种治疗方式的决定应由专家中心的多学科团队做出。

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