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采用体表标志定位技术行股外侧皮神经阻滞对减少植皮术后阿片类药物用量无效:一项回顾性病例对照研究。

Use of lateral femoral cutaneous nerve blocks by landmark technique is ineffective in decreasing narcotic usage after skin grafts: A retrospective case-control study.

机构信息

University of South Alabama College of Medicine, 5795 USA Drive North, CSAB 170, Mobile, AL 36688, USA.

University of South Alabama College of Medicine, Division of Trauma, Acute Care Surgery, and Burns, Department of Surgery, 2451 University Hospital Drive, Mobile, AL 36617, USA.

出版信息

Burns. 2024 May;50(4):997-1002. doi: 10.1016/j.burns.2024.01.006. Epub 2024 Jan 15.

Abstract

INTRODUCTION

Cutaneous burns are commonly treated with autologous skin grafts. Following skin grafting, many patients complain of pain at the donor site. Donor sites are taken most commonly from the lateral thigh, which is innervated by the lateral femoral cutaneous nerve (LFCN). Use of a LFCN blocks should decrease nociception from the donor site.

METHODS

Our group began utilizing LFCN blocks in 2019. Utilizing anatomic landmarks, LFCN blocks were performed on all patients who received autologous skin grafts to reduce perioperative pain. A retrospective cohort study was performed on all patients with 10% or less total body surface areas burns who received an autologous skin graft. A similar cohort from 2016, prior to use of any local or regional analgesia, was used as a historical control. Post-operative enteral and parenteral narcotic analgesics were collected for each post-operative day up to day 5 or discharge (whichever came first) and converted to morphine milligram equivalents (MME) to quantify analgesia after surgery.

RESULTS

Chart review identified 55 patients in the 2020 cohort. Fifty-five patients from the 2016 cohort were matched based upon size of skin graft, total body surface area (TBSA) burned, gender, and age. There were no statistically significant differences between the two groups in terms of size of graft, TBSA burned, age, gender, or type of burn. When examining narcotics usage in the immediate perioperative period (days 0-2), we found no difference between the two groups for total MME (113 vs 133, p = 0.28) or IV MME (38 vs 33, p = 0.45). Similar relationships existed in the extended post-operative period (days 1-5) for total MME (149 vs. 188, t = 0.22) or IV MME (37 vs. 50, t = 0.25). Examining daily narcotic usage also yielded no statistically different values.

CONCLUSION

Our data shows that use of LFCN block by landmark technique did not reduce narcotic usage in patients that undergo skin grafting procedures. Future studies should consider ultrasound-guided LFCN blocks.

摘要

引言

皮肤烧伤通常采用自体皮移植治疗。在植皮后,许多患者会抱怨供区疼痛。供区最常取自大腿外侧,由股外侧皮神经(LFCN)支配。使用 LFCN 阻滞可以减少供区的伤害感受。

方法

我们小组于 2019 年开始使用 LFCN 阻滞。利用解剖学标志,对所有接受自体皮移植的患者进行 LFCN 阻滞,以减轻围手术期疼痛。对所有接受 10%或以下全身体表面积烧伤的患者进行回顾性队列研究,这些患者接受了自体皮移植。使用 2016 年之前未使用任何局部或区域镇痛的相似队列作为历史对照。收集每个术后日(术后第 5 天或出院日,以先到者为准)的术后肠内和肠外阿片类镇痛药,并转换为吗啡毫克当量(MME)以量化术后的镇痛效果。

结果

图表回顾确定了 2020 年队列中的 55 名患者。根据皮瓣大小、全身体表面积(TBSA)烧伤面积、性别和年龄,从 2016 年队列中匹配了 55 名患者。两组在皮瓣大小、TBSA 烧伤面积、年龄、性别或烧伤类型方面无统计学差异。在研究围手术期即刻(第 0-2 天)的阿片类药物使用情况时,我们发现两组患者的总 MME(113 对 133,p=0.28)或 IV MME(38 对 33,p=0.45)均无差异。在术后延长期间(第 1-5 天)也存在类似的关系,总 MME(149 对 188,t=0.22)或 IV MME(37 对 50,t=0.25)。对每日阿片类药物使用量的检查也没有得出统计学上有差异的值。

结论

我们的数据表明,使用地标技术的 LFCN 阻滞并没有减少接受皮瓣移植手术患者的阿片类药物使用量。未来的研究应考虑超声引导下的 LFCN 阻滞。

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