Suppr超能文献

改良型叶片:硬质支气管镜治疗不可切除良性气管狭窄的介入选择

Modified blade: an interventional option in rigid bronchoscopy for non-resectable benign tracheal stenosis.

机构信息

Thoracic Surgery Unit, Università Degli Studi Della Campania "Luigi Vanvitelli", Via Pansini 5, 80131, Naples, Campania, Italy.

Highly Specialized Medical-Surgical Department, Università Degli Studi Della Campania "Luigi Vanvitelli", Naples, Campania, Italy.

出版信息

J Cardiothorac Surg. 2024 Feb 8;19(1):73. doi: 10.1186/s13019-024-02576-3.

Abstract

INTRODUCTION

Benign tracheobronchial stenosis is a abnormal tracheal lumen narrowing that may incur progressive dyspnea and life-threatening hypoxemia. There is no consensus on which patients should be treated with endoscopic or surgical method. This study investigates the outcomes of bronchoscopic dilatation in the treatment of benign tracheal stenosis using a device equipped with a blade to cut the stenotic lesions with dense fibrosis.

MATERIALS AND METHODS

The procedure was carried out in an operating room under general anesthesia. All patients were intubated with a Rigid Bronchoscope (RB) placed just above the stenosis. Through Rigid Bronchoscopy combined modalities were used as needed: radial incisions of the mucosal stenosis with blade at the levels of 4, 8 and 12 o'clock, with back and forth movements, then the stenotic area was dilated more easily with a rigid bronchoscope. Dilatation was performed by passing the RB of increasing diameter through stenotic areas and then Balloon dilatation of increasing diameter. There were no complications during the procedure.

RESULT

We conducted an observational, retrospective, single-centre study in the Thoracic Surgery Unit of the University of 'Luigi Vanvitelli' of Naples from November 2011 to September 2021. We included all consecutive patients with benign tracheal stenosis inoperable. During the study period, 113 patients were referred to our department with benign tracheal stenosis inoperable. 61 patients were treated with the blade. During the follow-up, a recurrence of the stenosis was observed in 8 patients in the first month and in 4 patients in the third month. Instead in the patients treated with the use of laser (52 patients), during the follow-up a recurrence was observed in 16 patients in the first month and in 6 patients in the third month; no patient relapsed after 6 months and after 1 year. Long term successful bronchoscopic management with blade was attained by 99% in simple and 93% in mixed stenosis and in complex type stenosis.

CONCLUSION

Our study underlines the importance of the use of the blade in bronchoscopic treatment as a valid conservative approach in the management of patients with inoperable benign tracheal stenosis as an alternative to the use of the laser, reducing the abnormal inflammatory reaction in order to limit recurrences.

摘要

介绍

良性气管支气管狭窄是一种气管管腔异常狭窄,可导致进行性呼吸困难和危及生命的低氧血症。对于应采用内镜还是手术方法治疗,目前尚无共识。本研究旨在探讨使用配备刀片的设备对伴有致密纤维化的狭窄病变进行切割以治疗良性气管狭窄的支气管扩张术的治疗效果。

材料与方法

该操作在手术室全身麻醉下进行。所有患者均使用刚性支气管镜(RB)在狭窄上方进行插管。通过刚性支气管镜检查,结合其他必要手段:在 4、8 和 12 点钟位置用刀片对黏膜狭窄处进行放射状切开,然后来回移动,然后用刚性支气管镜更容易地扩张狭窄区域,然后用刚性支气管镜通过逐渐增大直径的方式对狭窄区域进行扩张,随后再用球囊进行扩张。在操作过程中无并发症发生。

结果

我们在那不勒斯 Luigi Vanvitelli 大学胸外科进行了一项观察性、回顾性、单中心研究,研究时间为 2011 年 11 月至 2021 年 9 月。我们纳入了所有无法手术的良性气管狭窄的连续患者。在研究期间,共有 113 例无法手术的良性气管狭窄患者被转至我科。其中 61 例患者使用刀片进行治疗。在随访期间,8 例患者在第 1 个月和 4 例患者在第 3 个月出现狭窄复发。相比之下,在使用激光治疗的 52 例患者中,在随访期间,16 例患者在第 1 个月和 6 例患者在第 3 个月出现狭窄复发;6 个月和 1 年后均无患者复发。在单纯性狭窄和混合性狭窄中,99%的患者和复杂性狭窄中 93%的患者通过支气管镜下使用刀片治疗达到了长期的成功,且无复发。

结论

我们的研究强调了在支气管镜治疗中使用刀片的重要性,这是一种有效的保守治疗方法,可替代激光治疗,减少异常炎症反应,从而限制复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ced0/10851474/61ec1e1585a9/13019_2024_2576_Fig1_HTML.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验