Delisle M B, Netter J C, Peyrille F, Bouissou H
Ann Pathol. 1985;5(4-5):313-7.
Leigh's disease is a subacute metabolic encephalopathy characterized by bilateral and symmetrical lesions of basal ganglia, mid-brain and pons. Lesions are related to an abnormal pyruvate metabolism which mechanisms remain still uncertain. This disease is rare and the authors present a case with complete anatomic study.
Leigh病是一种亚急性代谢性脑病,其特征为基底节、中脑和脑桥的双侧对称性病变。病变与丙酮酸代谢异常有关,但其机制仍不明确。这种疾病很罕见,作者报告了一例进行了完整解剖学研究的病例。