Department of Oral and Maxillofacial Surgery, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Int J Implant Dent. 2024 Feb 9;10(1):8. doi: 10.1186/s40729-024-00522-5.
Reconstruction with vascularized bone grafts after ablative surgery and subsequent dental rehabilitation with implants is often challenging; however, it helps improve the patient's quality of life. This retrospective case-control study aimed to determine the implant survival/success rates in different vascularized bone grafts and potential risk factors.
Only patients who received implants in free vascularized bone grafts between 2012 and 2020 were included. The free flap donor sites were the fibula, iliac crest, and scapula. The prosthetic restoration had to be completed, and the observation period had to be over one year after implantation. Implant success was defined according to the Health Scale for Dental Implants criteria.
Sixty-two patients with 227 implants were included. The implant survival rate was 86.3% after an average of 48.7 months. The causes of implant loss were peri-implantitis (n = 24), insufficient osseointegration (n = 1), removal due to tumor recurrence (n = 1), and osteoradionecrosis (n = 5). Of all implants, 52.4% were classified as successful, 19.8% as compromised, and 27.8% as failed. Removal of osteosynthesis material prior to or concurrent with implant placement resulted in significantly better implant success than material not removed (p = 0.035). Localization of the graft in the mandibular region was associated with a significantly better implant survival (p = 0.034) and success (p = 0.002), also a higher Karnofsky Performance Status Scale score with better implant survival (p = 0.014).
Implants placed in vascularized grafts showed acceptable survival rates despite the potential risk factors often present in these patient groups. However, peri-implantitis remains a challenge.
在消融手术后使用带血管的骨移植物进行重建,随后进行种植体的牙齿修复通常具有挑战性;然而,它有助于提高患者的生活质量。本回顾性病例对照研究旨在确定不同带血管骨移植物中的种植体存活率/成功率和潜在的危险因素。
仅纳入 2012 年至 2020 年间接受游离血管化骨移植物中种植体的患者。游离皮瓣供区为腓骨、髂嵴和肩胛骨。必须完成修复体的修复,并且种植体植入后观察期必须超过一年。根据种植牙健康量表标准定义种植体成功。
共纳入 62 例患者,227 枚种植体。平均随访 48.7 个月后,种植体存活率为 86.3%。种植体丢失的原因包括种植体周围炎(n=24)、骨整合不足(n=1)、因肿瘤复发而移除(n=1)和骨放射性坏死(n=5)。所有种植体中,52.4%被归类为成功,19.8%为受损,27.8%为失败。在植入种植体之前或同时移除骨内固定材料的患者,其种植体成功率显著优于未移除材料的患者(p=0.035)。移植部位位于下颌区域与种植体存活率(p=0.034)和成功率(p=0.002)显著相关,Karnofsky 表现状态评分较高也与种植体存活率相关(p=0.014)。
尽管这些患者群体中存在潜在的危险因素,但植入带血管的移植物的种植体显示出可接受的存活率。然而,种植体周围炎仍然是一个挑战。